Results 141 to 150 of about 4,741,341 (392)

Multistable switches and their role in cellular differentiation networks

open access: yesBMC Bioinformatics, 2014
Cellular differentiation during development is controlled by gene regulatory networks (GRNs). This complex process is always subject to gene expression noise.
Ahmadreza Ghaffarizadeh   +2 more
semanticscholar   +1 more source

Indirect Organogenesis of Calendula officinalis L. and Comparative Phytochemical Studies of Field-Grown and In Vitro-Regenerated Tissues

open access: yesAgronomy
Calendula officinalis L. is an important medicinal and ornamental plant possessing multiple bioactive compounds. The in vitro plant regeneration method has recently replaced traditional field cultivation practices of calendula due to its fascinating ...
Tooba Fatima   +4 more
doaj   +1 more source

Some Causes Underlying Cellular Differentiation [PDF]

open access: yes, 1958
Author Institution: Department of Botany and Plant Pathology, Ohio State University, Columbus ...
Popham, Richard A.
core  

The light and shadow of senescence and inflammation in cardiovascular pathology and regenerative medicine [PDF]

open access: yes, 2017
Recent epidemiologic studies evidence a dramatic increase of cardiovascular diseases, especially associated with the aging of the world population. During aging, the progressive impairment of the cardiovascular functions results from the compromised ...
Cavarretta, Elena   +9 more
core   +4 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Hijacking the Cellular Mail: Exosome Mediated Differentiation of Mesenchymal Stem Cells

open access: yesStem Cells International, 2016
Bone transplantation is one of the most widely performed clinical procedures. Consequently, bone regeneration using mesenchymal stem cells and tissue engineering strategies is one of the most widely researched fields in regenerative medicine.
Raghuvaran Narayanan   +2 more
semanticscholar   +1 more source

Structural Equation Modeling and Whole-Genome Scans Uncover Chromosome Regions and Enriched Pathways for Carcass and Meat Quality in Beef

open access: yesFrontiers in Genetics, 2018
Structural equation models involving latent variables are useful tools for formulating hypothesized models defined by theoretical variables and causal links between these variables.
Joel D. Leal-Gutiérrez   +7 more
doaj   +1 more source

Diversity, Stability, Recursivity, and Rule Generation in Biological System: Intra-inter Dynamics Approach

open access: yes, 1998
Basic problems for the construction of a scenario for the Life are discussed. To study the problems in terms of dynamical systems theory, a scheme of intra-inter dynamics is presented.
Kaneko K.   +7 more
core   +2 more sources

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