Results 181 to 190 of about 1,589,246 (309)

Cellular prion protein expression in astrocytes modulates neuronal survival and differentiation [PDF]

, 2007
Flávia Regina Souza Lima, C Arantes, Angelita Muras, Regina Nomizo, Helena Brentani, Vilma R. Martins   +5 more
openalex   +1 more source

Effects of somatic mutations on cellular differentiation in iPSC models of neurodevelopment [PDF]

, 2022
Pau Puigdevall, Julie Jerber, Petr Danecek, Sergi Castellano, Helena Kilpinen   +4 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Data-driven inference of Boolean networks from transcriptomes to predict cellular differentiation and reprogramming. [PDF]

NPJ Syst Biol Appl
Chevalier S, Becker J, Gui Y, Noël V, Su C, Jung S, Calzone L, Zinovyev A, Del Sol A, Pang J, Sinkkonen L, Sauter T, Paulevé L.   +12 more
europepmc   +1 more source

A segmentation clock patterns cellular differentiation in a bacterial biofilm. [PDF]

Cell, 2022
Chou KT, Lee DD, Chiou JG, Galera-Laporta L, Ly S, Garcia-Ojalvo J, Süel GM.   +6 more
europepmc   +1 more source

Additional file 2: of Exploring transcriptomic diversity in muscle revealed that cellular signaling pathways mainly differentiate five Western porcine breeds

, 2015
Magali SanCristobal, Florian Rohart, Christine Lascor, Marcel Bouffaud, Lidwine Trouilh, Pascal G.P. Martin, Yannick Lippi, Thierry Tribout, Thomas Faraut, M. J. Mercat, Denis Milan, Laurence Liaubet   +11 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Nuclear envelope and chromatin choreography direct cellular differentiation. [PDF]

Nucleus
Nair A, Khanna J, Kler J, Ragesh R, Sengupta K.   +4 more
europepmc   +1 more source

Correction: MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF. [PDF]

Cell Death Differ, 2022
Wang X, Ros U, Agrawal D, Keller EC, Slotta-Huspenina J, Dill V, Shen B, Shi R, Herold T, Belka C, Mishra R, Bassermann F, Garcia-Saez AJ, Jost PJ.   +13 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source