Results 181 to 190 of about 1,468,423 (351)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Chromatin loop dynamics during cellular differentiation are associated with changes to both anchor and internal regulatory features. [PDF]

Genome Res, 2023
Bond ML, Davis ES, Quiroga IY, Dey A, Kiran M, Love MI, Won H, Phanstiel DH.   +7 more
europepmc   +1 more source

The metabolism of macromolecules during the differentiation of myxamoebae of the cellular slime mould Dictyostelium discoideum containing different amounts of glycogen [PDF]

, 1974
B.D. Hames, John Ashworth
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

MIF-like domain containing protein orchestrates cellular differentiation and virulence in the fungal pathogen Magnaporthe oryzae. [PDF]

iScience, 2023
Galli M, Jacob S, Zheng Y, Ghezellou P, Gand M, Albuquerque W, Imani J, Allasia V, Coustau C, Spengler B, Keller H, Thines E, Kogel KH.   +12 more
europepmc   +1 more source

The Appearance and Disappearance of Uridine Diphosphate Glucose Pyrophosphorylase Activity during Differentiation of the Cellular Slime Mold Dictyostelium discoideum

, 1967
John Ashworth, Maurice Sussman
openalex   +1 more source

Gonadal Hormones and Brain Development: Cellular Aspects of Sexual Differentiation [PDF]

, 1978
C. Dominique Toran‐Allerand
openalex   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Editorial: Mechanisms of cellular differentiation, organ development, and novel model systems. [PDF]

Front Cell Dev Biol, 2022
Hendriks D, Artegiani B, Kretzschmar K.
europepmc   +1 more source

Enzyme synthesis in the cellular slime mould Dictyostelium discoideum during the differentiation of myxamoebae grown axenically [PDF]

, 1972
J. Quance, John Ashworth
openalex   +1 more source