Results 211 to 220 of about 4,342,740 (357)

DNA methylation patterns contribute to changes of cellular differentiation pathways in leukocytes with LOY from patients with Alzheimer´s disease. [PDF]

Cell Mol Life Sci
Jąkalski M, Bruhn-Olszewska B, Rychlicka-Buniowska E, Davies H, Sarkisyan D, Siedlar M, Baran J, Węglarczyk K, Jaszczynski J, Ryś J, Gedraitis V, Filipowicz N, Klich-Rączka A, Kilander L, Ingelsson M, Dumanski JP.   +15 more
europepmc   +1 more source

Elevation of CD4+ Differentiated Memory T Cells Is Associated With Acute Cellular and Antibody-Mediated Rejection After Liver Transplantation [PDF]

, 2013
Undine A. Gerlach, Katrin Vogt, Stephan Schlickeiser, Christian Meisel, Mathias Streitz, Désirée Kunkel, Christine Appelt, Stefanie Ahrlich, Nils Lachmann, P. Neuhaus, Andreas Pascher, Birgit Sawitzki   +11 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

PIWI pathway: bridging acute myeloid leukemia stemness and cellular differentiation. [PDF]

Front Cell Dev Biol
Garcia-Silva MR, Márquez ME, Pinello N.
europepmc   +1 more source

Mutations that disrupt PHOXB interaction with the neuronal calcium sensor HPCAL1 impede cellular differentiation in neuroblastoma [PDF]

, 2013
Wenqi Wang, Quan Zhong, Lisong Teng, Namrata Bhatnagar, Bhuvanesh Kumar Sharma, Xin Zhang, William Luther, Lee P. Haynes, Robert D. Burgoyne, Marc Vidal, Samuel L. Volchenboum, David E. Hill, Richard E. George   +12 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Gene module reconstruction identifies cellular differentiation processes and the regulatory logic of specialized secretion in zebrafish. [PDF]

Dev Cell
Wang Y, Liu J, Du LY, Wyss JL, Farrell JA, Schier AF.   +5 more
europepmc   +1 more source

Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer

Cell, 2015
L. Dow, K. O’Rourke, Janelle Simon, Darjus F. Tschaharganeh, J. V. Es, H. Clevers, S. Lowe   +6 more
semanticscholar   +1 more source

Effects of transforming growth factor-beta on human lymphokine-activated killer cell precursors. Autocrine inhibition of cellular proliferation and differentiation to immune killer cells. [PDF]

, 1988
A Kasid, Gillian I. Bell, E P Director
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source