Results 211 to 220 of about 1,468,423 (351)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

A network based efficient drug repurposing strategy for targeting diabesity

Genes and Diseases, 2023
Subhajit Dutta, Ted Natoli, Deep Chanda, Sindhuja Rajavelu, Debojyoti De   +4 more
doaj  

Plasticity and the evolution of group-level regulation of cellular differentiation in the volvocine algae. [PDF]

Proc Biol Sci
Davison DR, Nedelcu AM, Eneji OA, Michod RE.   +3 more
europepmc   +1 more source

Heme-deficient metabolism and impaired cellular differentiation as an evolutionary trade-off for human infectivity in Trypanosoma brucei gambiense. [PDF]

Nat Commun, 2022
Horáková E, Lecordier L, Cunha P, Sobotka R, Changmai P, Langedijk CJM, Abbeele JVD, Vanhollebeke B, Lukeš J.   +8 more
europepmc   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Control of Cellular Differentiation Trajectories for Cancer Reversion. [PDF]

Adv Sci (Weinh)
Gong JR, Lee CK, Kim HM, Kim J, Jeon J, Park S, Cho KH.   +6 more
europepmc   +1 more source

High Diversity of Glycosphingolipid Glycans of Colorectal Cancer Cell Lines Reflects the Cellular Differentiation Phenotype. [PDF]

Mol Cell Proteomics, 2022
Wang D, Wang D, Madunić K, Zhang T, Mayboroda OA, Lageveen-Kammeijer GSM, Wuhrer M.   +6 more
europepmc   +1 more source

Protein synthesis during development and differentiation in the cellular slime mould Dictyostelium discoideum [PDF]

, 1984
Donald J. Watts
openalex   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Genomes of Novel Myxococcota Reveal Severely Curtailed Machineries for Predation and Cellular Differentiation. [PDF]

Appl Environ Microbiol, 2021
Murphy CL, Yang R, Decker T, Cavalliere C, Andreev V, Bircher N, Cornell J, Dohmen R, Pratt CJ, Grinnell A, Higgs J, Jett C, Gillett E, Khadka R, Mares S, Meili C, Liu J, Mukhtar H, Elshahed MS, Youssef NH.   +19 more
europepmc   +1 more source