Orally Bioavailable GSK-3α/β Dual Inhibitor Increases Markers of Cellular Differentiation In Vitro and Bone Mass In Vivo [PDF]
Nalini H. Kulkarni +13 more
openalex +1 more source
Most autophagic cell death studies lack evidence of causality
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley +1 more source
DNA methylation patterns contribute to changes of cellular differentiation pathways in leukocytes with LOY from patients with Alzheimer´s disease. [PDF]
Jąkalski M +15 more
europepmc +1 more source
Phylotranscriptomics points to multiple independent origins of multicellularity and cellular differentiation in the volvocine algae. [PDF]
Lindsey CR, Rosenzweig F, Herron MD.
europepmc +1 more source
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura +7 more
wiley +1 more source
PIWI pathway: bridging acute myeloid leukemia stemness and cellular differentiation. [PDF]
Garcia-Silva MR, Márquez ME, Pinello N.
europepmc +1 more source
Effects of transforming growth factor-beta on human lymphokine-activated killer cell precursors. Autocrine inhibition of cellular proliferation and differentiation to immune killer cells. [PDF]
A Kasid, Gillian I. Bell, E P Director
openalex +1 more source
Key role for inhibins in effective T cell activation, migration and Th17 differentiation
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco +5 more
wiley +1 more source
Gene module reconstruction identifies cellular differentiation processes and the regulatory logic of specialized secretion in zebrafish. [PDF]
Wang Y +5 more
europepmc +1 more source

