Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu+9 more
wiley +1 more source
Regulatory complexity of cellular differentiation in Candida albicans revealed through systematic screening of protein kinase mutants. [PDF]
Lorenz MC.
europepmc +1 more source
scInTime: A Computational Method Leveraging Single-Cell Trajectory and Gene Regulatory Networks to Identify Master Regulators of Cellular Differentiation. [PDF]
Xu Q+7 more
europepmc +1 more source
Characterization of ribosome heterogeneity during endothelial to hematopoietic transition
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian+4 more
wiley +1 more source
Epigenetic Clues to Better Understanding of the Asexual Embryogenesis in planta and in vitro
Taras Pasternak, Denes Dudits
doaj +1 more source
Epac activation reduces trans-endothelial migration of undifferentiated neuroblastoma cells and cellular differentiation with a CDK inhibitor further enhances Epac effect. [PDF]
Inuwa RF, Moss D, Quayle J, Swadi R.
europepmc +1 more source
Myofibroblasts and Fibrosis: Mitochondrial and Metabolic Control of Cellular Differentiation. [PDF]
Gibb AA, Lazaropoulos MP, Elrod JW.
europepmc +1 more source
Regulation of the Macroautophagic Machinery, Cellular Differentiation, and Immune Responses by Human Oncogenic γ-Herpesviruses. [PDF]
Münz C.
europepmc +1 more source
Adeno-associated virus type 2-mediated transduction in primary human bone marrow-derived CD34+ hematopoietic progenitor cells: donor variation and correlation of transgene expression with cellular differentiation [PDF]
Selvarangan Ponnazhagan+9 more
openalex +1 more source