Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Loss of Cell-Cell Contact Inhibits Cellular Differentiation of α-Catenin Knock Out P19 Embryonal Carcinoma Cells and Their Colonization into the Developing Mouse Embryos. [PDF]
Sato M, Inada E, Kubota N, Ozawa M.
europepmc +1 more source
Chromatin-Associated Membraneless Organelles in Regulation of Cellular Differentiation. [PDF]
Grosch M +3 more
europepmc +1 more source
Relevance of Major Histocompatibility Complex Class II Expression as a Hallmark for the Cellular Differentiation in the Human Adrenal Cortex1 [PDF]
Christian Marx +5 more
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The contributions of DNA accessibility and transcription factor occupancy to enhancer activity during cellular differentiation. [PDF]
Long T +6 more
europepmc +1 more source
Surface sensing stimulates cellular differentiation in Caulobacter crescentus. [PDF]
Snyder RA +5 more
europepmc +1 more source
Chromatin modifiers and remodellers: regulators of cellular differentiation
Taiping Chen, Sharon Y. R. Dent
semanticscholar +1 more source

