Results 111 to 120 of about 864,406 (289)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Organic Matter Preservation and Incipient Mineralization of Microtubules in 120 Ma Basaltic Glass

Frontiers in Earth Science, 2019
Hollow tubular structures in subaqueously-emplaced basaltic glass may represent trace fossils caused by microbially-mediated glass dissolution. Mineralized structures of similar morphology and spatial distribution in ancient, metamorphosed basaltic rocks
Matthew R. M. Izawa, Matthew R. M. Izawa, James J. Dynes, Neil R. Banerjee, Roberta L. Flemming, Lachlan C. W. MacLean, Callum J. Hetherington, Sergei Matveev, Gordon Southam   +8 more
doaj   +1 more source

A practical review on the measurement tools for cellular adhesion force

, 2019
Cell cell and cell matrix adhesions are fundamental in all multicellular organisms. They play a key role in cellular growth, differentiation, pattern formation and migration.
Gerecsei, Tamas, Horvath, Robert, Orgovan, Norbert, Peter, Beatrix, Szabo, Balint, Ungai-Salanki, Rita   +5 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

NON-CONVENTIONAL COLD PREPARATION OF CELLULAR GLASS UNDER ECONOMICAL AND ENVIRONMENTALLY FRIENDLY CONDITIONS

Nonconventional Technologies Review
Peculiarities of the modern cellular concrete manufacturing technique were borrowed in the expanding glass technique at ambient temperature presented in the work. Using aluminum dust in calcium hydroxide solution and adding carboxymethyl cellulose (CMC)
Lucian Paunescu, Sorin Mircea Axinte, Eniko Volceanov, Bogdan Valentin Paunescu   +3 more
doaj  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Realistic Tunneling States for the Magnetic Effects in Non-Metallic Real Glasses

, 2015
The discovery of magnetic and compositional effects in the low temperature properties of multi-component glasses has prompted the need to extend the standard two-level systems (2LSs) tunneling model.
Abragam A., Ashcroft N.W., Bakai A.S., Fleischmann A., Giancarlo Jug, Gurevich V.L., Lebedev A.A., Lebedev A.A., Randall J.T., Sciortino F., Shelby J.E., Silvia Bonfanti, Smolyakov B.P., Walter Kob   +13 more
core   +3 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Enzyme-free release of adhered cells from standard culture dishes using intermittent ultrasonic traveling waves. [PDF]

, 2019
Cell detachment is essential in culturing adherent cells. Trypsinization is the most popular detachment technique, even though it reduces viability due to the damage to the membrane and extracellular matrix.
Friend, James, Hirano, Makoto, Imashiro, Chikahiro, Kurashina, Yuta, Kuribara, Taiki, Ohnuma, Kiyoshi, Takemura, Kenjiro, Totani, Kiichiro   +7 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source