Results 1 to 10 of about 510,776 (366)

Pyrogallol-Phloroglucinol-6, 6-Bieckol Restored Primary Cilia Length, Which Was Decreased by High-Fat Diet in Visceral Adipose Tissue, and Decreased Adipogenesis

open access: yesInternational Journal of Endocrinology, 2022
Length of primary cilia, which involves cell cycle reentry and disassembly of cilia, promotes cell mitosis. It is known that the cilia length in adipose tissue of the high-fat diet (HFD) animals was shortened and accompanied by increased adipogenesis ...
Seyeon Oh   +5 more
doaj   +1 more source

Molecular Biology in Glioblastoma Multiforme Treatment

open access: yesCells, 2022
Glioblastoma (GBM, grade IV astrocytoma), the most frequently occurring primary brain tumor, presents unique challenges to therapy due to its location, aggressive biological behavior, and diffuse infiltrative growth, thus contributing to having ...
Claudia Abbruzzese   +3 more
doaj   +1 more source

Myristoylated, alanine-rich C-kinase substrate (MARCKS) regulates toll-like receptor 4 signaling in macrophages

open access: yesScientific Reports, 2023
MARCKS (myristoylated alanine-rich C-kinase substrate) is a membrane-associated protein expressed in many cell types, including macrophages. MARCKS is functionally implicated in cell adhesion, phagocytosis, and inflammation.
Jiraphorn Issara-Amphorn   +6 more
doaj   +1 more source

An Alternative Splice Variant of HIPK2 with Intron Retention Contributes to Cytokinesis

open access: yesCells, 2020
HIPK2 is a DYRK-like kinase involved in cellular stress response pathways, development, and cell division. Two alternative splice variants of HIPK2, HIPK2-FL and HIPK2-Δe8, have been previously identified as having different protein stability but ...
Veronica Gatti   +9 more
doaj   +1 more source

Radiofrequency Irradiation Modulates TRPV1-Related Burning Sensation in Rosacea

open access: yesMolecules, 2021
Rosacea is a skin inflammatory condition that is accompanied by not only redness and flushing but also unseen symptoms, such as burning, stinging, and itching. TRPV1 expression in UVB-exposed skin can lead to a painful burning sensation.
Seyeon Oh   +4 more
doaj   +1 more source

Repurposing chlorpromazine in the treatment of glioblastoma multiforme: analysis of literature and forthcoming steps

open access: yesJournal of Experimental & Clinical Cancer Research, 2020
Background Glioblastoma multiforme is a CNS cancer characterized by diffuse infiltrative growth, aggressive clinical behavior and very poor prognosis.
Claudia Abbruzzese   +4 more
doaj   +1 more source

Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways

open access: yesmSystems, 2021
Pattern recognition receptors (PRRs) form the front line of defense against pathogens. Many of the molecular mechanisms that facilitate PRR signaling have been characterized in detail, which is critical for the development of accurate PRR pathway models ...
Nathan P. Manes, Aleksandra Nita-Lazar
doaj   +1 more source

Tackling the Behavior of Cancer Cells: Molecular Bases for Repurposing Antipsychotic Drugs in the Treatment of Glioblastoma

open access: yesCells, 2022
Glioblastoma (GBM) is associated with a very dismal prognosis, and current therapeutic options still retain an overall unsatisfactorily efficacy in clinical practice.
Michele Persico   +7 more
doaj   +1 more source

Spatial spectrum and energy efficiency of random cellular networks [PDF]

open access: yes, 2015
It is a great challenge to evaluate the network performance of cellular mobile communication systems. In this paper, we propose new spatial spectrum and energy efficiency models for Poisson-Voronoi tessellation (PVT) random cellular networks. To evaluate
Ge, X   +11 more
core   +1 more source

Analysis and evaluation of distance-to-mean broadcast method for VANET

open access: yesJournal of King Saud University: Computer and Information Sciences, 2014
Multi-hop broadcast is a critical component in embedded communication systems. Some vehicular ad-hoc network (VANET) applications in particular use broadcast communications extensively.
Michael Slavik   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy