Results 11 to 20 of about 432,489 (267)
Background Glioblastoma multiforme is a CNS cancer characterized by diffuse infiltrative growth, aggressive clinical behavior and very poor prognosis.
Claudia Abbruzzese +4 more
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Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways
Pattern recognition receptors (PRRs) form the front line of defense against pathogens. Many of the molecular mechanisms that facilitate PRR signaling have been characterized in detail, which is critical for the development of accurate PRR pathway models ...
Nathan P. Manes, Aleksandra Nita-Lazar
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Glioblastoma (GBM) is associated with a very dismal prognosis, and current therapeutic options still retain an overall unsatisfactorily efficacy in clinical practice.
Michele Persico +7 more
doaj +1 more source
Hypergraphs and Cellular Networks
3,41Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany, 2Institute for Mathematical Optimization, Faculty of Mathematics, Otto-von-Guericke University Magdeburg, Magdeburg, Germany, 3Institute for Bioinformatics and Systems Biology, Helmholtz Zentrum Mu¨nchen—German Research Center forEnvironmental Health, Neuherberg ...
Steffen Klamt +2 more
openaire +5 more sources
Analysis and evaluation of distance-to-mean broadcast method for VANET
Multi-hop broadcast is a critical component in embedded communication systems. Some vehicular ad-hoc network (VANET) applications in particular use broadcast communications extensively.
Michael Slavik +2 more
doaj +1 more source
The renin–angiotensin system is involved in the development of hypertension and sarcopenia. Increased levels of angiotensin II (Ang II) lead to upregulation of Ang II type 1 receptor (AT1R), which results in increasing reactive oxygen species (ROS) by ...
Seyeon Oh +4 more
doaj +1 more source
Caveolin-1 (Cav-1) induces cellular senescence by reducing extracellular signal-regulated kinase (ERK)1/2 phosphorylation and activating p53 via inhibition of mouse double minute 2 homolog (MDM2) and sirtuin 1 (Sirt1), promoting cell cycle arrest and ...
Seyeon Oh +4 more
doaj +1 more source
Extrachromosomal Histone H2B Contributes to the Formation of the Abscission Site for Cell Division
Histones are constitutive components of nucleosomes and key regulators of chromatin structure. We previously observed that an extrachromosomal histone H2B (ecH2B) localizes at the intercellular bridge (ICB) connecting the two daughter cells during ...
Laura Monteonofrio +3 more
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Inferring cellular networks – a review [PDF]
In this review we give an overview of computational and statistical methods to reconstruct cellular networks. Although this area of research is vast and fast developing, we show that most currently used methods can be organized by a few key concepts. The first part of the review deals with conditional independence models including Gaussian graphical ...
Florian Markowetz, Rainer Spang
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Affordable Broad Agile Farming System for Rural and Remote Area
We develop a fast-deployed crop health monitoring system using state-of-the-art technologies to collect data from crop fields in order to take appropriate and timely actions.
Mohammad Ammad Uddin +4 more
doaj +1 more source

