Results 1 to 10 of about 51,331 (226)

Analysis of Pharmacokinetic and Pharmacodynamic Interactions Between Chlorpromazine and Risperidone via Simultaneous Measurement of Multiple Receptor Occupancy in the Rat Brain [PDF]

Biomedicines
Background/Objectives: Combination therapy for schizophrenia may exacerbate side effects mediated by multiple brain receptors. This study aimed to elucidate the pharmacodynamic and pharmacokinetic interactions between chlorpromazine and risperidone.
Gaku Akashita, Eriko Nakatani, Shimako Tanaka, Takashi Okura   +3 more
doaj   +2 more sources

Clinical Factors Influencing Improvement in Disorganization in Clinical High-Risk for Psychosis: Preliminary Findings From a 2-Year Follow-Up. [PDF]

Asia Pac Psychiatry
ABSTRACT Disorganization is under‐treated in early psychosis. We aimed at exploring clinical factors potentially improving disorganization in individuals at Clinical High Risk for Psychosis (CHR‐P) across 2 years of follow‐up. About 180 participants completed the GAF and the PANSS.
Pelizza L, Leuci E, Quattrone E, Occhionero M, Biancalani A, Palmisano D, Pupo S, Paulillo G, Pellegrini C, Pellegrini P, Menchetti M.   +10 more
europepmc   +2 more sources

Associations Between Serum Adipokine, Antipsychotic Exposure, and Clinical Characteristics in Chronic Schizophrenia: A Cross‐Sectional Study [PDF]

Neuropsychopharmacol Rep
In chronic schizophrenia, serum adiponectin levels were positively associated with antipsychotic dosage, particularly with multi‐acting receptor‐targeted antipsychotics and were influenced by gender and hospitalization period. These findings highlight gender‐specific metabolic regulation and the importance of monitoring adipokines during long‐term ...
Ohno Y, Saito K, Hanabusa K, Nakai A, Nagai T, Hida N, Sanada K.   +6 more
europepmc   +2 more sources

Evaluation of the use of chlorpromazine for agitation in pediatric patients [PDF]

Mental Health Clinician, 2023
Introduction: Chlorpromazine is a first-generation antipsychotic used for behavioral problems in pediatric patients. However, other therapies may demonstrate both improved outcomes and fewer side effects.
Rajwoana Ahmed, PharmD, Megan Maroney, PharmD, BCPP, Germin Fahim, PharmD, BCPS, Hoytin Lee Ghin, PharmD, BCPS, Andrew Scott Mathis, PharmD   +4 more
doaj   +1 more source

Evaluation the sedative and analgesic effects of tramadol and chlorpromazine alone or as a combination in chicks

Kufa Journal for Veterinary Medical Sciences, 2021
The goal of this study was to assess the pain-relieving action of tramadol alone or when administered with chlorpromazine and screening for analgesic effects by using sedative non-analgesic doses of tramadol and chlorpromazine when injected together in
Manahel Allawi Abdulla Aljbori, Rawnaq Faris Abdulqader Alshalchi, Ghada Abdulmunem Faris   +2 more
doaj   +1 more source

Anticancer Properties of the Antipsychotic Drug Chlorpromazine and Its Synergism With Temozolomide in Restraining Human Glioblastoma Proliferation In Vitro

Frontiers in Oncology, 2021
The extremely poor prognosis of patients affected by glioblastoma (GBM, grade IV glioma) prompts the search for new and more effective therapies. In this regard, drug repurposing or repositioning can represent a safe, swift, and inexpensive way to bring ...
S. Matteoni, P. Matarrese, B. Ascione, Mariachiara Buccarelli, L. Ricci-Vitiani, R. Pallini, V. Villani, A. Pace, M. G. Paggi, C. Abbruzzese   +9 more
semanticscholar   +1 more source

Coated Wire and Multiwalled Carbon Nanotube Composite Coated Wire Sensors for Determination of Chlorpromazine Hydrochloride in Pharmaceutical Preparations. [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2014
fabrication and performance characteristics of novel potentiometric sensors for the determination of chlorpromazine hydrochloride are described. The proposed sensors include a coated copper wire sensor and a multiwalled carbon nanotube (MWCNT) composite ...
Riyadh M. Jihad, Ismael K. Al-Hitti, Adawiya J. Hayder   +2 more
doaj   +1 more source

Quincke-edema induced by chlorpromazine: About two cases

European Psychiatry, 2021
Introduction Quincke-edema has been specifically associated with using certain drugs including chlorpromazine as detailed through two clinical cases. Objectives Illustration of two clinical cases about angioedema induced by Chlorpromazine.
S. Brahim, W. Bouali, M. Henia, A. Abid, L. Zarrouk   +4 more
doaj   +1 more source

Incidence of Orthostatic Hypotension in Schizophrenic Patients Using Antipsychotics at Sambang Lihum Mental Health Hospital, South Kalimantan

Borneo Journal of Pharmacy, 2021
Schizophrenia is a psychiatric disorder that requires antipsychotics therapy. Antipsychotics cause many side effects, including orthostatic hypotension.
Noor Cahaya, Sandra Putri Wijaya, Khoerul Anwar   +2 more
doaj   +1 more source

Short–term effect of chlorpromazine and diazepam on blood plasma acetylcholinesterase activity in chicks [PDF]

Iraqi Journal of Veterinary Sciences, 2007
The response of blood plasma acetylcholinestrase to acute administration of chlorpromazine and diazepam was examined in chick. Chlorpromazine in a dose–dependent manner at 25, 50, and 75 mg/Kg, subcutaneously inhibited the activity of Ache in the blood ...
L .K. Yacoub
doaj   +1 more source