Results 21 to 30 of about 36,001 (235)

Quetiapine Ameliorates MIA-Induced Impairment of Sensorimotor Gating: Focus on Neuron-Microglia Communication and the Inflammatory Response in the Frontal Cortex of Adult Offspring of Wistar Rats

Cells, 2022
The maternal immune activation produced by the systemic administration of lipopolysaccharide (LPS) in rats provides valuable insights into the basis of behavioural schizophrenia-like disturbances and biochemical changes in the brains of the offspring ...
Katarzyna Chamera, Katarzyna Curzytek, Kinga Kamińska, Ewa Trojan, Agnieszka Basta-Kaim   +4 more
doaj   +1 more source

Dynamic Changes in Plasma Metabolic Profiles Reveal a Potential Metabolite Panel for Interpretation of Fatal Intoxication by Chlorpromazine or Olanzapine in Mice

Metabolites, 2022
Diagnosing the cause of fatal intoxication by antipsychotic agents is an important task in forensic practice. In the 2020 Annual Report of the American Association of Poison Control Centers, among 40 deaths caused by antipsychotics, 21 cases were ...
Rui Bai, Xiaohui Dai, Xingang Miao, Bing Xie, Feng Yu, Bin Cong, Di Wen, Chunling Ma   +7 more
doaj   +1 more source

Chlorpromazine versus placebo for schizophrenia [PDF]

, 2014
BACKGROUND: Chlorpromazine, formulated in the 1950s, remains a benchmark treatment for people with schizophrenia.OBJECTIVES: To review the effects of chlorpromazine compared with placebo, for the treatment of schizophrenia.SEARCH METHODS: We searched the
Adams, Clive E.
core   +3 more sources

Chlorpromazine Efficiently Treats the Crisis of Pheochromocytoma: Four Case Reports and Literature Review

Frontiers in Cardiovascular Medicine, 2021
Pheochromocytoma multisystem crisis (PMC) is a potentially lethal emergency due to catecholamine secretion. The condition manifests as severe hypertension to intractable cardiogenic shock and has a high mortality rate.
James Jiqi Wang, James Jiqi Wang, Zuowen He, Zuowen He, Yan Yang, Bo Yu, Bo Yu, Hong Wang, Hong Wang, Hu Ding, Hu Ding, Guanglin Cui, Guanglin Cui, Luyun Wang, Luyun Wang, Dao Wen Wang, Dao Wen Wang, Jiangang Jiang, Jiangang Jiang   +18 more
doaj   +1 more source

Salivary flow rate and decayed, missing, and filled teeth (DMFT) in female patients with schizophrenia on chlorpromazine therapy

Journal of Dental Sciences, 2013
Background/purpose: The purpose of the study was to investigate relationship between saliva flow rates, estrogen levels, and caries prevalence in female psychiatric patients under antipsychotic therapy.
Jelena Krunić, Nikola Stojanović, Nedeljka Ivković, Dragica Stojić   +3 more
doaj   +1 more source

Chlorpromazine versus thiothixene for people with schizophrenia (Protocol) [PDF]

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To review the effects of chlorpromazine compared with thiothixene for people with ...
Dutton, Brittany, Wakeham, Joseph, Wildman, Levine, Cardosa, Daniel, Shaw, Philippa Amy   +4 more
core   +1 more source

The Effects of Chlorpromazine on Reproductive System and Function in Female Rats [PDF]

International Journal of Fertility and Sterility, 2015
Background Chlorpromazine (CPZ), an antipsychotic drug, is associated with increased risk of sexual dysfunction through increasing prolactin levels. The current study evaluates the effect of CPZ-induced hyperprolactinemia on ovarian follicular growth ...
Zahra Zamani, Samad Zare, Rajabali Sadrkhanlou, Abbas Ahmadi, Elham Movahed   +4 more
doaj   +1 more source

Chlorpromazine for psychosis induced aggression or agitation [PDF]

, 2010
Background Agitated or violent behaviour constitutes 10% of all emergency psychiatric treatment. Some guidelines do not recommend the use of chlorpromazine for rapid tranquillisation but it is still often used for this purpose.
Adams, Clive E., Jones, Hannah F.
core   +1 more source

Testing the Protective Effects of Sulfobutylether-Βeta-Cyclodextrin (SBECD) and Sugammadex against Chlorpromazine-Induced Acute Toxicity in SH-SY5Y Cell Line and in NMRI Mice

Pharmaceutics, 2022
Chlorpromazine (CPZ) is an antipsychotic drug which can cause several adverse effects and drug poisoning. Recent studies demonstrated that CPZ forms highly stable complexes with certain cyclodextrins (CDs) such as sulfobutylether-β-CD (SBECD) and ...
Eszter Fliszár-Nyúl, Rita Csepregi, Gábor Benkovics, Lajos Szente, Miklós Poór   +4 more
doaj   +1 more source

Development and Evaluation of an FDM Printed Nasal Device for CPZ Solid Nanoparticles

Molecules, 2023
Nasal drug delivery has been a focus of scientific interest for decades. A number of drug delivery systems and devices are available and have been highly successful in providing better and more comfortable therapy. The benefits of nasal drug delivery are
Thinh To Quoc, Krisztina Bíró, Ágota Pető, Dóra Kósa, Dávid Sinka, István Lekli, Attila Kiss-Szikszai, István Budai, Mónika Béres, Miklós Vecsernyés, Pálma Fehér, Ildikó Bácskay, Zoltán Ujhelyi   +12 more
doaj   +1 more source