Double gene overexpression of ZNF746 and cellular prion protein in rat adipose-derived mesenchymal stromal cell therapy protects the liver against ischemia‒reperfusion injury. [PDF]
Ko SF +4 more
europepmc +1 more source
Wnt, glucocorticoid and cellular prion protein cooperate to drive a mesenchymal phenotype with poor prognosis in colon cancer. [PDF]
Mouillet-Richard S +21 more
europepmc +1 more source
The role of cellular prion protein in lipid metabolism in the liver. [PDF]
Arora AS +10 more
europepmc +1 more source
Lack of cellular prion protein causes Amyloid β accumulation, increased extracellular vesicle abundance, and changes to exosome biogenesis proteins. [PDF]
Johansson L +5 more
europepmc +1 more source
The 37kDa/67kDa Laminin Receptor LRP/LR as a molecular target in neurodegenerative diseases [PDF]
Pflanz, Heike
core
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Preventing Prion Pathogenicity by Targeting the Cellular Prion Protein
Infectious Disorders - Drug Targets, 2009Prions are unique in that the infectious particles contain no detectable nucleic acid and appear to consist of aggregated forms of misfolded cellular prion protein. Prions form distinct strains and can transmit disease between species. Whilst the molecular basis of prion diseases is beginning to be unravelled, much remains unknown including the atomic ...
Andrew J, Nicoll, John, Collinge
openaire +2 more sources
Cellular prion protein neuroprotective function: implications in prion diseases
Journal of Molecular Medicine, 2004Prion protein can display two conformations: a normal cellular conformation (PrP) and a pathological conformation associated with prion diseases (PrP(Sc)). Three complementary strategies are used by researchers investigating how PrP is involved in the pathogenesis of prion diseases: elucidation of the normal function of PrP, determination of how PrP(Sc)
Xavier, Roucou, Andréa C, LeBlanc
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