Results 1 to 10 of about 2,490 (115)

Interspecies Transmission from Pigs to Ferrets of Antigenically Distinct Swine H1 Influenza A Viruses with Reduced Reactivity to Candidate Vaccine Virus Antisera as Measures of Relative Zoonotic Risk

Viruses, 2022
During the last decade, endemic swine H1 influenza A viruses (IAV) from six different genetic clades of the hemagglutinin gene caused zoonotic infections in humans.
J. Brian Kimble, Carine K. Souza, Tavis K. Anderson, Zebulun W. Arendsee, David E. Hufnagel, Katharine M. Young, Nicola S. Lewis, C. Todd Davis, Sharmi Thor, Amy L. Vincent Baker   +9 more
doaj   +1 more source

Transmission of Raccoon-Passaged Chronic Wasting Disease Agent to White-Tailed Deer

Viruses, 2022
The transmission characteristics of prion diseases are influenced by host prion protein sequence and, therefore, the host species. Chronic wasting disease (CWD), a prion disease of cervids, has widespread geographical distribution throughout North ...
Eric D. Cassmann, Alexis J. Frese, S. Jo Moore, Justin J. Greenlee   +3 more
doaj   +1 more source

Machine Learning Prediction and Experimental Validation of Antigenic Drift in H3 Influenza A Viruses in Swine

mSphere, 2021
Influenza A viruses (IAV) in swine constitute a major economic burden to an important global agricultural sector, impact food security, and are a public health threat.
Michael A. Zeller, Phillip C. Gauger, Zebulun W. Arendsee, Carine K. Souza, Amy L. Vincent, Tavis K. Anderson   +5 more
doaj   +1 more source

Changes in the Hemagglutinin and Internal Gene Segments Were Needed for Human Seasonal H3 Influenza A Virus to Efficiently Infect and Replicate in Swine

Pathogens, 2022
The current diversity of influenza A viruses (IAV) circulating in swine is largely a consequence of human-to-swine transmission events and consequent evolution in pigs.
Daniela S. Rajao, Eugenio J. Abente, Joshua D. Powell, Marcus J. Bolton, Phillip C. Gauger, Bailey Arruda, Tavis K. Anderson, Troy C. Sutton, Daniel R. Perez, Amy L. Vincent Baker   +9 more
doaj   +1 more source

Comparison of the Transcriptome Response within the Swine Tracheobronchial Lymphnode Following Infection with PRRSV, PCV-2 or IAV-S.

Pathogens, 2020
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major respiratory pathogen of swine that has become extremely costly to the swine industry worldwide, often causing losses in production and animal life due to their ease of spread. However,
Laura C. Miller, Damarius S. Fleming, Kelly M. Lager   +2 more
doaj   +1 more source

Characterization of Senecavirus A Isolates Collected From the Environment of U.S. Sow Slaughter Plants

Frontiers in Veterinary Science, 2022
Vesicular disease caused by Senecavirus A (SVA) is clinically indistinguishable from foot-and-mouth disease (FMD) and other vesicular diseases of swine. When a vesicle is observed in FMD-free countries, a costly and time-consuming foreign animal disease ...
Kyle S. Hoffman, Nicki L. Humphrey, John A. Korslund, Tavis K. Anderson, Kay. S. Faaberg, Kelly M. Lager, Alexandra C. Buckley   +6 more
doaj   +1 more source

Pathologic and biochemical characterization of PrPSc from elk with PRNP polymorphisms at codon 132 after experimental infection with the chronic wasting disease agent

BMC Veterinary Research, 2018
Background The Rocky Mountain elk (Cervus elaphus nelsoni) prion protein gene (PRNP) is polymorphic at codon 132, with leucine (L132) and methionine (M132) allelic variants present in the population.
S. Jo Moore, Catherine E. Vrentas, Soyoun Hwang, M. Heather West Greenlee, Eric M. Nicholson, Justin J. Greenlee   +5 more
doaj   +1 more source

Bovine adapted transmissible mink encephalopathy is similar to L-BSE after passage through sheep with the VRQ/VRQ genotype but not VRQ/ARQ

BMC Veterinary Research, 2020
Background Transmissible mink encephalopathy (TME) is a fatal neurologic disease of farmed mink. Evidence indicates that TME and L-BSE are similar and may be linked in some outbreaks of TME.
Eric Cassmann, Sarah Jo Moore, Robyn Kokemuller, Anne Balkema-Buschmann, Martin Groschup, Eric Nicholson, Justin Greenlee   +6 more
doaj   +1 more source

Expression Pattern of a Mini Human PrP Gene Promoter in Transgenic Mice

Neurobiology of Disease, 2002
The prion protein is central to the pathogenesis of prion diseases, although its exact function remains unclear. Although transgenic mice have been widely utilised in prion research, their PrP expression patterns have not been characterised in detail. We
E.A. Asante, I. Gowland, J.M. Linehan, S.P. Mahal, J. Collinge   +4 more
doaj   +1 more source

Genetic and Antigenic Characterization of an Expanding H3 Influenza A Virus Clade in U.S. Swine Visualized by Nextstrain

mSphere, 2022
Defining factors that influence spatial and temporal patterns of influenza A virus (IAV) is essential to inform vaccine strain selection and strategies to reduce the spread of potentially zoonotic swine-origin IAV.
Megan N. Neveau, Michael A. Zeller, Bryan S. Kaplan, Carine K. Souza, Phillip C. Gauger, Amy L. Vincent, Tavis K. Anderson   +6 more
doaj   +1 more source