Results 1 to 10 of about 16,279 (223)
The emergence of classical BSE from atypical/Nor98 scrapie
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance The origin of transmissible BSE in cattle remains unestablished. Sheep scrapie is a potential source of this known zoonotic. Here we investigated the capacity of sheep scrapie to propagate in bovine PrP transgenic mice.
Douet Jy +2 more
exaly +2 more sources
Animal, 2016 Scrapie is a naturally occurring transmissible spongiform encephalopathy in sheep and goat. It has been known for ~250 years and is characterised by the accumulation of an abnormal isoform of a host-encoded prion protein that leads to progressive ...
L. Curcio +4 more
doaj +2 more sources
Diversity in Neuroanatomical Distribution of Abnormal Prion Protein in Atypical Scrapie
PLoS Pathogens, 2007 Scrapie is a transmissible spongiform encephalopathy (TSE) in sheep and goats. In recent years, atypical scrapie cases were identified that differed from classical scrapie in the molecular characteristics of the disease-associated pathological prion ...
Cord Drogemuller +2 more
exaly +2 more sources
Evidence in sheep for pre-natal transmission of scrapie to lambs from infected mothers.
PLoS ONE, 2013 Natural scrapie transmission from infected ewes to their lambs is thought to occur by the oral route around the time of birth. However the hypothesis that scrapie transmission can also occur before birth (in utero) is not currently favoured by most ...
James D Foster +2 more
doaj +2 more sources
Veterinary Research, 2012 Susceptibility of sheep to scrapie, a transmissible spongiform encephalopathy of small ruminants, is strongly influenced by polymorphisms of the prion protein gene (PRNP).
Acutis Pier Luigi +15 more
doaj +2 more sources
Animals, 2021 Simple Summary Classical scrapie is a prionic, neurological, consumptive, and chronic disease that affects naturally domestic small ruminants. It was initially described in the UK, and since then it has spread throughout the world.
C. Acín +12 more
semanticscholar +1 more source
BSE can propagate in sheep co-infected or pre-infected with scrapie
Scientific Reports, 2021 To understand the possible role of mixed-prion infections in disease presentation, the current study reports the co-infection of sheep with bovine spongiform encephalopathy (BSE) and scrapie.
Angela Chong +10 more
doaj +1 more source
Evolutionary biology and the risk of scrapie disease in sheep [PDF]
Open Veterinary Journal, 2018 Scrapie in sheep occurs in two forms. Classical scrapie, along with chronic wasting disease in deer, differs from all other prion diseases in being contagious and occurring as propagating epidemics.
David Bruce Adams
doaj +1 more source
Diagnosis in Scrapie: Conventional Methods and New Biomarkers
Pathogens, 2023 Scrapie, a naturally occurring prion disease affecting goats and sheep, comprises classical and atypical forms, with classical scrapie being the archetype of transmissible spongiform encephalopathies.
Diego Sola +12 more
doaj +1 more source
Prion Evolvability and the Hazard of Atypical Scrapie in Small Ruminants
Open Veterinary Science, 2020 Observations on strain behaviour and direct demonstrations of natural selection establish that the scrapie agent and prions in general are able to evolve.
Adams David B.
doaj +1 more source