Results 21 to 30 of about 29,784 (268)

A quantitative assessment of the amount of prion diverted to category 1 materials and wastewater during processing [PDF]

, 2013
In this article the development and parameterization of a quantitative assessment is described that estimates the amount of TSE infectivity that is present in a whole animal carcass (bovine spongiform encephalopathy [BSE] for cattle and classical ...
Adkin, Arnold, Arnold, Benestad, Casalone, Comer, Cooper, Cummins, Daly, Det Norske Veritas, Det Norske Veritas, Det Norske Veritas, Det Norske Veritas, Detwiler, Fediaevsky, Fryer, Gale, Gale, Groschup, Groschup, Hadlow, Hadlow, Kimberlin, Prendergast, Prendergast, Simmons, Terry, Warriss, Wells   +28 more
core   +1 more source

The prevalence of atypical scrapie in sheep from positive flocks is not higher than in the general sheep population in 11 European countries

BMC Veterinary Research, 2010
Background During the last decade, active surveillance for transmissible spongiform encephalopathies in small ruminants has been intensive in Europe. In many countries this has led to the detection of cases of atypical scrapie which, unlike classical ...
Liam Barry, Hautaniemi Maria, Poizat Renaud, Orge Leonor, Thorgeirsdottir Stefania, Ingravalle Francesco, Nöremark Maria, Maurella Cristiana, Fediaevsky Alexandre, Calavas Didier, Ru Giuseppe, Hopp Petter   +11 more
doaj   +1 more source

PrPCWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer [PDF]

, 2002
Up to 15% of free-ranging mule deer in northeastern Colorado and southeastern Wyoming, USA, are afflicted with a prion disease, or transmissible spongiform encephalopathy (TSE), known as chronic wasting disease (CWD).
Barillas-Mury, C., Hoover, E.A., Keulen, L.J.M., van, Langeveld, J.P.M., Miller, M.W., Oesch, B., Sigurdson, C.J.   +6 more
core   +2 more sources

The emergence of classical BSE from atypical/Nor98 scrapie

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance The origin of transmissible BSE in cattle remains unestablished. Sheep scrapie is a potential source of this known zoonotic. Here we investigated the capacity of sheep scrapie to propagate in bovine PrP transgenic mice.
Alvina Huor, J. Espinosa, E. Vidal, H. Cassard, Jean-Yves Douet, Séverine Lugan, Naima Aron, A. Marín-Moreno, P. Lorenzo, P. Aguilar-Calvo, J. Badiola, R. Bolea, M. Pumarola, S. Benestad, L. Orge, A. Thackray, R. Bujdoso, J. Torres, O. Andréoletti   +18 more
semanticscholar   +1 more source

Monitoring of clinical signs in goats with transmissible spongiform encephalopathies

BMC Veterinary Research, 2010
Background As there is limited information about the clinical signs of BSE and scrapie in goats, studies were conducted to describe the clinical progression of scrapie and BSE in goats and to evaluate a short clinical protocol for its use in detecting ...
Goldmann Wilfred, Sisó Sílvia, González Lorenzo, Simmons Marion M, Phelan Laura J, Bone Gemma E, Konold Timm, Cawthraw Saira, Hawkins Steve AC   +8 more
doaj   +1 more source

Potential scrapie-associated polymorphisms of the prion protein gene (PRNP) in Korean native black goats

Scientific Reports, 2019
Small ruminants, including sheep and goats are natural hosts of scrapie, and the progression of scrapie pathogenesis is strongly influenced by polymorphisms in the prion protein gene (PRNP).
Seonkwan Kim, Yong-Chan Kim, Sae-Young Won, B. Jeong   +3 more
semanticscholar   +1 more source

Norwegian farmers' vigilance in reporting sheep showing scrapie-associated signs

BMC Veterinary Research, 2007
Background Scrapie is a chronic neurodegenerative disease affecting small ruminants and belongs to the transmissible spongiform encephalopathies. Scrapie is considered a serious animal disease and it has been notifiable in Norway since 1965. The clinical
Jarp Jorun, Vatn Synnøve, Hopp Petter
doaj   +1 more source

Evaluation of Antemortem Diagnostic Techniques in Goats Naturally Infected With Scrapie

Frontiers in Veterinary Science, 2020
Scrapie is a naturally occurring transmissible spongiform encephalopathy (TSE) that affects sheep and goats. Sheep and goats can be infected with scrapie as lambs or kids via contact with the placenta or placental fluids, or from ingestion of prions shed
Najiba Mammadova, M. Heather West Greenlee, S. Jo Moore, Soyoun Hwang, Aaron D. Lehmkuhl, Eric M. Nicholson, Justin J. Greenlee   +6 more
doaj   +1 more source

Transmission of the atypical/Nor98 scrapie agent to Suffolk sheep with VRQ/ARQ, ARQ/ARQ, and ARQ/ARR genotypes.

PLoS ONE, 2021
Scrapie is a transmissible spongiform encephalopathy that occurs in sheep. Atypical/Nor98 scrapie occurs in sheep that tend to be resistant to classical scrapie and it is thought to occur spontaneously.
Eric D Cassmann, Najiba Mammadova, S Jo Moore, Sylvie Benestad, Justin J Greenlee   +4 more
doaj   +1 more source

Review: Update on Classical and Atypical Scrapie in Sheep and Goats

Veterinary Pathology-Supplement, 2018
Scrapie is a naturally occurring transmissible spongiform encephalopathy (TSE) or prion disease of sheep and goats. Scrapie is a protein misfolding disease where the normal prion protein (PrPC) misfolds into a pathogenic form (PrPSc) that is highly ...
J. Greenlee
semanticscholar   +1 more source