Results 31 to 40 of about 12,794 (224)

Low-volume goat milk transmission of classical scrapie to lambs and goat kids. [PDF]

PLoS ONE, 2018
The risk of classical scrapie transmission in small ruminants is highest during the neonatal period with the placenta recognized as a significant source of infection.
Sally A Madsen-Bouterse, Margaret A Highland, Rohana P Dassanayake, Dongyue Zhuang, David A Schneider   +4 more
doaj   +1 more source

Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom [PDF]

, 2011
The application of genetic breeding programmes to eradicate transmissible spongiform encephalopathies in goats is an important aim for reasons of animal welfare as well as human food safety and food security. Based on the positive impact of Prnp genetics
Bossers, A., Windl, O., González Lorenzo, James Foster, Parnham David, Foster James, Alex Bossers, Ryan, K., Goldmann Wilfred, Ginny Saunders, Xicohtencatl Rosa, Kelly Ryan, Paula Stewart, Wilfred Goldmann, Lorenzo González, Foster, J., David Parnham, Stewart Paula, Goldmann, W., Nora Fernandez, A., B., Rosa Xicohtencatl, Fernandez Nora, Bossers Alex, Parnham, D., Saunders, G., Stewart, P., Xicohtencatl, R., Fernandez, N., Windl Otto, Gonzalez, L., Ryan Kelly, Saunders Ginny, Otto Windl   +33 more
core   +1 more source

Clinical findings in two cases of atypical scrapie in sheep: a case report

BMC Veterinary Research, 2007
Background Atypical scrapie is a recently recognised form of transmissible spongiform encephalopathy of sheep that differs from classical scrapie in its neuropathological and biochemical features.
Chaplin Melanie, Everitt Sharon, Bracegirdle John, Bone Gemma, Davis Andrew, Konold Timm, Saunders Ginny C, Cawthraw Saira, Simmons Marion M   +8 more
doaj   +1 more source

White-Tailed Deer Prion Protein Gene Variability Suggests Selection Against Chronic Wasting Disease in Canada’s Prairies

Viruses
Chronic wasting disease (CWD), a transmissible spongiform encephalopathy that targets cervids, has become a significant threat to both free-ranging and captive populations of Canadian white-tailed deer.
William Pilot, Maria I. Arifin, Antanas Staskevicius, Nicholas J. Haley, Gordon Mitchell, Jiewen Guan   +5 more
doaj   +1 more source

Implications of conflicting associations of the prion protein (PrP) gene with scrapie susceptibility and fitness on the persistence of scrapie.

PLoS ONE, 2009
BackgroundExisting mathematical models for scrapie dynamics in sheep populations assume that the PrP gene is only associated with scrapie susceptibility and with no other fitness related traits.
Andrea Doeschl-Wilson, Rami Sawalha, Simon Gubbins, Beatriz Villanueva   +3 more
doaj   +1 more source

State-of-the-art review of goat TSE in the European Union, with special emphasis on PRNP genetics and epidemiology [PDF]

, 2009
Scrapie is a fatal, neurodegenerative disease of sheep and goats. It is also the earliest known member in the family of diseases classified as transmissible spongiform encephalopathies (TSE) or prion diseases, which includes Creutzfeldt-Jakob disease in ...
Olivier Andreéoletti, Groschup, Martin H., Simone Peletto, Foster, James, Barillet, F., Acin, Cristina, Pierluigi Acutis, Peletto, S., Langeveld, J., Theodoros Sklaviadis, Keulen, L.J.M., van, Bossers, Alex, Vaccari, G., Van Keulen, Lucien, Foster, J., Acin, C., Cristina Acin, Andreoletti, O., Jan Langeveld, Goldmann, Wilfred, Umberto Agrimi, Sklaviadis, T., Vaccari, Gabriele, Langeveld, Jan, van Keulen, L., Groschup, M.H., Peletto, Simone, Bossers, A., Gabriele Vaccari, James Foster, Panagiotidis, C.H., Cynthia H. Panagiotidis, Alex Bossers, Badiola, J. J., Badiola, J.J., van Keulen, L.J.M., Juan J. Badiola, Francis Barillet, Sklaviadis, Theodoros, Barillet, Francis, Langeveld, J.P.M., Wilfred Goldmann, Panagiotidis, Cynthia H., Acutis, Pierluigi, Andreeoletti, O., Badiola, Juan J., Goldmann, W., Panagiotidis, C. H., Groschup, M. H., Andreoletti, Olivier, Acutis, P., Agrimi, Umberto, Lucien Van Keulen, Martin H. Groschup, Agrimi, U.   +54 more
core   +1 more source

Breeding with resistant rams leads to rapid control of classical scrapie in affected sheep flocks

, 2011
Susceptibility to scrapie, a transmissible spongiform encephalopathy in sheep, is modulated by the genetic make-up of the sheep. Scrapie control policies, based on selecting animals of resistant genotype for breeding, have recently been adopted by the ...
van Roermund, H.J.W., Bas Engel, Lucien JM van Keulen, Roermund, H.J.W., van, Gonnie Nodelijk, van Roermund Herman JW, Vellema, P., Herman JW van Roermund, Vellema Piet, Engel, B., Thomas J Hagenaars, Nodelijk Gonnie, Engel Bas, Keulen, L.J.M., van, Hagenaars, T.H.J., van Keulen, L.J.M., Nodelijk, G., Piet Vellema, Hagenaars Thomas J, van Keulen Lucien JM   +19 more
core   +1 more source

Scrapie versus Chronic Wasting Disease in White-Tailed Deer

Emerging Infectious Diseases
White-tailed deer are susceptible to scrapie (WTD scrapie) after oronasal inoculation with the classical scrapie agent from sheep. Deer affected by WTD scrapie are difficult to differentiate from deer infected with chronic wasting disease (CWD).
Zoe J. Lambert, Jifeng Bian, Eric D. Cassmann, M. Heather West Greenlee, Justin J. Greenlee   +4 more
doaj   +1 more source

Transmissibility of atypical scrapie in ovine transgenic mice: major effects of host prion protein expression and donor prion genotype. [PDF]

PLoS ONE, 2009
Atypical scrapie or Nor98 has been identified as a transmissible spongiform encephalopathy (TSE) that is clearly distinguishable from classical scrapie and BSE, notably regarding the biochemical features of the protease-resistant prion protein PrP(res ...
Jean-Noël Arsac, Dominique Bétemps, Eric Morignat, Cécile Féraudet, Anna Bencsik, Denise Aubert, Jacques Grassi, Thierry Baron   +7 more
doaj   +1 more source

Eradication of scrapie with selective breeding: are we nearly there?

, 2010
Background Following EU decision 2003/100/EC Member States have recently implemented sheep breeding programmes to reduce the prevalence of sheep with TSE susceptible prion genotypes.
Bossers, A., Fred G van Zijderveld, Melchior, M.B., Bossers Alex, Windig, J.J., Davidse, A., Melchior Marielle B, Alex Bossers, Thomas J Hagenaars, Jack J Windig, Windig Jack J, Aart Davidse, Hagenaars, T.H.J., van Zijderveld, F.G., Marielle B Melchior, Zijderveld, F.G., van, Hagenaars Thomas J, Davidse Aart, van Zijderveld Fred G   +18 more
core   +1 more source