Results 171 to 180 of about 114,739 (248)

Mapping Cellular Reprogramming via Pooled Overexpression Screens with Paired Fitness and Single-Cell RNA-Sequencing Readout [PDF]

, 2018
Udit Parekh, Yan Wu, Dongxin Zhao, Atharv Worlikar, Neha Shah, Kun Zhang, Prashant Mali   +6 more
openalex   +1 more source

Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian, Siya Dai, Chunyi Guo, Wenjun Wang, Jiajia Pang, Yichen Shen, Mingyuan Xu, Jie Hu, Wenguo Cui, Xiaoming Sun, Jinghong Xu   +10 more
wiley   +1 more source

Epigenetic and Cellular Reprogramming of Doxorubicin-Resistant MCF-7 Cells Treated with Curcumin. [PDF]

Int J Mol Sci
Poma P, Rigogliuso S, Labbozzetta M, Nicosia A, Costa S, Ragusa MA, Notarbartolo M.   +6 more
europepmc   +1 more source

MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming. [PDF]

Commun Biol, 2023
Mohammed Ismail W, Mazzone A, Ghiraldini FG, Kaur J, Bains M, Munankarmy A, Bagwell MS, Safgren SL, Moore-Weiss J, Buciuc M, Shimp L, Leach KA, Duarte LF, Nagi CS, Carcamo S, Chung CY, Hasson D, Dadgar N, Zhong J, Lee JH, Couch FJ, Revzin A, Ordog T, Bernstein E, Gaspar-Maia A.   +24 more
europepmc   +1 more source

Time-course transcriptome analysis of human cellular reprogramming from multiple cell types reveals the drastic change occurs between the mid phase and the late phase [PDF]

, 2018
Akihiro Kuno, Ken Nishimura, Satoru Takahashi   +2 more
openalex   +1 more source

SGLT2 Inhibitors Produce Cardiorenal Benefits by Promoting Adaptive Cellular Reprogramming to Induce a State of Fasting Mimicry: A Paradigm Shift in Understanding Their Mechanism of Action [PDF]

, 2020
Milton Packer
openalex   +1 more source

M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration

Advanced Science, EarlyView.
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao, Yijia Yin, Fangyuan Shuai, Waishan Lam, Tao Zhou, Yaxin Xie, Xuesong He, Xianglong Han   +7 more
wiley   +1 more source

Integrating Prime Editing and Cellular Reprogramming as Novel Strategies for Genetic Cardiac Disease Modeling and Treatment. [PDF]

Curr Cardiol Rep
Yao B, Lei Z, Gonçalves MAFV, Sluijter JPG.   +3 more
europepmc   +1 more source

Updated Perspectives on Direct Vascular Cellular Reprogramming and Their Potential Applications in Tissue Engineered Vascular Grafts. [PDF]

J Funct Biomater, 2022
Sellahewa SG, Li JY, Xiao Q.
europepmc   +1 more source

Role of SUMO-Specific Protease 2 in Reprogramming Cellular Glucose Metabolism

, 2013
Shuang Tang, Gang Huang, Xuemei Tong, Lian Xu, Rong Cai, Jie Li, Xiang Zhou, Shaoli Song, Chen Huang, Jinke Cheng   +9 more
openalex   +2 more sources