Results 251 to 260 of about 224,348 (348)

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Glutathione accelerates the cell cycle and cellular reprogramming in plant regeneration. [PDF]

Dev Cell
Lee LR, Guillotin B, Rahni R, Hutchison C, Desvoyes B, Gutierrez C, Birnbaum KD.   +6 more
europepmc   +1 more source

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

AI Revolutionizes Cellular Reprogramming of Periodontal Ligament. [PDF]

Int Dent J
Yadalam PK, Munivel S, Ardila CM.
europepmc   +1 more source

Additional file 10: of Long non-coding RNAs potentially function synergistically in the cellular reprogramming of SCNT embryos

, 2018
Fengrui Wu, Yong Liu, Qingqing Wu, Dengkun Li, Ling Zhang, Xiaoqing Wu, Rong Wang, Di Zhang, Shaorong Gao, Wenyong Li   +9 more
openalex   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Embryonic stem cells and nuclear transfer strategies - Present state and future prospects [PDF]

, 2000
Beier, Henning M., Wobus, Anna M., Wolf, Eckhard   +2 more
core   +1 more source

Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface. [PDF]

Nat Commun
Broich L, Wullenkord H, Osman MK, Fu Y, Müsken M, Reuther P, Brönstrup M, Sieben C.   +7 more
europepmc   +1 more source

Acid and the basis for cellular plasticity and reprogramming in gastric repair and cancer

, 2018
José B. Sáenz, Jason C. Mills
openalex   +2 more sources

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source