Results 261 to 270 of about 224,348 (348)

Reprogrammed quiescent B cells provide an effective cellular therapy against chronic experimental autoimmune encephalomyelitis

, 2011
Elisabeth Calderón‐Gómez, Vicky Lampropoulou, Ping Shen, Patrícia Neves, Toralf Roch, Ulrik Stervbo, Sascha Rutz, Anja A. Kühl, Frank L. Heppner, Christoph Loddenkemper, Stephen M. Anderton, Jean Kanellopoulos, Pierre Charneau, Simon Fillatreau   +13 more
openalex   +2 more sources

Cellular Reprogramming: Chromatin Puts On the Brake [PDF]

, 2011
Piali Sengupta, Tim Schedl
openalex   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Editorial: Targeting cellular signalling pathways for disease therapy: the potential of cellular reprogramming and protein kinase inhibitors. [PDF]

Front Pharmacol
Marensi V, Oliveira PF, Zamoner A.
europepmc   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Oxidative stress and reprogramming of mitochondrial function and dynamics as targets to modulate cancer cell behavior and chemoresistance [PDF]

, 2019
Domenicotti, C, Falone, S, Lisanti, MP
core   +3 more sources

Epigenetic and Cellular Reprogramming of Doxorubicin-Resistant MCF-7 Cells Treated with Curcumin. [PDF]

Int J Mol Sci
Poma P, Rigogliuso S, Labbozzetta M, Nicosia A, Costa S, Ragusa MA, Notarbartolo M.   +6 more
europepmc   +1 more source

662 Reprogramming of cutaneous keratinocytes by the regenerative transcription factor Pitx1 alters the cellular landscape of the skin and promotes wound healing [PDF]

Andrew M. Overmiller, Akihiko Uchiyama, Emma Hope, C. O'Neill, S. Nayak, K. Hasneen, Stefania Dell’Orso, S. Brooks, M.I. Morasso   +8 more
openalex   +1 more source

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

A New Frontier in Tumor Eradication: Harnessing <i>In Vivo</i> Cellular Reprogramming for Durable Cancer Immunotherapy. [PDF]

Cell Reprogram
Chronis C.
europepmc   +1 more source