Living unicellular eukaryote Tetrahymena pyriformis as a model for study of mitochondrial energetics in mammalian cells under conditions of reduced oxidative metabolism. [PDF]
, 2010 Some “animal-like” protozoa are used instead of mammalian cells in diverse investigations. _Tetrahymena pyriformis_ cells in stationary phase of growth and washed from oxidative substrates (_T.pyriformis_) function under conditions of ...
Elena Mokhova
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Hormone deprivation alters mitochondrial function and lipid profile in the hippocampus [PDF]
, 2017 Mitochondrial dysfunction is a common hallmark in aging. In the female, reproductive senescence is characterized by loss of ovarian hormones, many of whose neuroprotective effects converge upon mitochondria.
Alvarez, Silvia +7 more
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Cellular Respiration in Intermittent Magnetic Fields.
Experimental Biology and Medicine, 1967 SummaryTable I details the individual data on response of the different tissues (except the HeLa cells) to the magnetic fields.
M R, Pereira +3 more
openaire +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Ageing as a price of cooperation and complexity: Self-organization of complex systems causes the ageing of constituent networks [PDF]
, 2008 The analysis of network topology and dynamics is increasingly used for the description of the structure, function and evolution of complex systems.
Á +6 more
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Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Targeting of reactive isolevuglandins in mitochondrial dysfunction and inflammation. [PDF]
, 2019 Inflammation is a major cause of morbidity and mortality in Western societies. Despite use of multiple drugs, both chronic and acute inflammation still represent major health burdens.
Amarnath, Venkataraman +10 more
core
Mechanism of endocarp-imposed constraints of germination of Lannea microcarpa seeds [PDF]
, 2008 Lannea microcarpa, a multipurpose tree species from the dry African savanna, sheds seeds that often display inhibition of germination. The underlying mechanism was investigated using seeds processed from fully matured fruits collected from natural stands
Golovina, E.A., Hoekstra, F.A., Neya, O.
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Caffeine impairs hl-60 cellular respiration
Hamdan Medical Journal, 2009 We investigated the effect of caffeine on mitochondrial O2 consumption in human promyelocytic leukemia (HL-60) cells. A phosphorescence analyzer that measures O2 concentrations in cell suspensions as function of time was used for this purpose. O2 concentrations were determined from the phosphorescence of Pd phosphor, calculated by fitting the ...
Eyone Jones +2 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source