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The rise of cellular therapy

Transfusion and Apheresis Science, 2011
In 1938, the field of Transfusion Medicine began as the simpler entity - Blood Banking. It was a discipline that focused on collecting, processing, storing and distributing end stage blood cells, plasma and plasma fractions to patients. Over the years, the field progressed to include clinical patient services such as apheresis technology and with the ...
Jacquelyn, Choate, Edward L, Snyder
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Cellular Engineering and Cellular Therapies — An Overview

2003
Cellular therapy offers a challenging approach for the treatment of a variety of diseases. Although some types of cellular therapy, like the generation and application of appropriately differentiated embryonic or adult stem cells, still await the successful outcome of a lot of further experiments, others have been established and clinically applied ...
de Leij, LFMH   +2 more
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Cellular Gene Therapy

Hematology/Oncology Clinics of North America, 1995
During the last decade, molecular genetic techniques have been used increasingly to transfer human genes into mammalian cells, to correct and enhance cell function, and finally to treat human disease. Despite the current obstacles to developing even the simplest therapeutic strategy, gene therapy promises to have an almost unlimited future. The ability
J H, Lee, H G, Klein
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Adoptive Cellular Therapy

2010
Cell-based therapies with various lymphocytes and antigen-presenting cells are promising approaches for cancer immunotherapy. The transfusion of T lymphocytes, also called adoptive cell therapy (ACT), is an effective treatment for viral infections, has induced regression of cancer in early stage clinical trials, and may be a particularly important and ...
Stephan A, Grupp, Carl H, June
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Remyelination: Cellular and gene therapy

Seminars in Pediatric Neurology, 1998
Dysfunctional myelination or oligodendroglial abnormalities play a prominent role in a vast array of pediatric neurological diseases of genetic, inflammatory, immunological, traumatic, ischemic, developmental, metabolic, and infectious causes. Recent advances in glial cell biology have suggested that effective remyelination strategies may, indeed, be ...
L L, Billinghurst   +2 more
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Cellular Engineering and Cellular Therapies

2003
Cellular Engineering and Cellular Therapies - an Overview.- Gene Therapy 2002: A New Start.- Stem Cells: Potential, Selection and Plasticity.- The Potential of Stem Cell Transplantation to Rescue the Failing Liver.- The New Regulatory Environment for Cellular Therapy Products: Challenges for Academic-Based Manufacturing Facilities.- Biological ...
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Regulation of cellular therapy in Australia

Pathology, 2011
Use of cellular products for therapeutic purposes has predominantly been unregulated in Australia until recently. Transplant of haemopoietic progenitor cells (HPC) for bone marrow regeneration is now a routine treatment for many disorders with an established mechanism of facility accreditation.
Annette E, Trickett, Dominic M, Wall
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Voluntary accreditation of cellular therapies: Foundation for the Accreditation of Cellular Therapy (FACT)

Cytotherapy, 2003
Voluntary accreditation of cells, tissues, and cellular and tissue-based products intended for human transplantation is an important mechanism for improving quality in cellular therapy. The Foundation for the Accreditation of Cellular Therapy (FACT) has developed and implemented programs of voluntary inspection and accreditation for hematopoietic ...
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Cellular Therapy for Advanced Melanoma

Surgical Clinics of North America
Cellular therapy has been an evolving therapeutic approach in advanced melanoma over the past 40 y. The first tumor infiltrating lymphocyte (TIL) therapy, lifileucil, was Food and Drug Administration-approved in 2024 for patients with metastatic melanoma who have previously been treated with an anti-PD-1 therapy and BRAF inhibitor (BRAF V600 mutant ...
Jacob, Zaemes, Geoffrey T, Gibney
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Cellular pathways of recombinant adeno-associated virus production for gene therapy

Biotechnology Advances, 2021
Sha Sha   +2 more
exaly  

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