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Adoptive Immunotherapy for Cancer or Viruses [PDF]
Annual Review of Immunology, 2014 Adoptive immunotherapy, or the infusion of lymphocytes, is a promising approach for the treatment of cancer and certain chronic viral infections. The application of the principles of synthetic biology to enhance T cell function has resulted in substantial increases in clinical efficacy.
Marcela V Maus +2 more
exaly +3 more sources
Adoptive T Cell Immunotherapy for Cancer [PDF]
Rambam Maimonides Medical Journal, 2015 Harnessing the immune system to recognize and destroy tumor cells has been the central goal of anti-cancer immunotherapy. In recent years, there has been an increased interest in optimizing this technology in order to make it a clinically feasible ...
Karlo Perica +3 more
doaj +3 more sources
Applied Bionics and Biomechanics, 2022 Objective. To explore the differential efficacy of chemoradiotherapy combined with adoptive immunotherapy and radiochemotherapy alone in patients with non-small-cell lung cancer (NSCLC). Methods.
Zhiming Fan, Honggui He, Liqun Chen
doaj +1 more source
Neoantigen‐reactive T cell: An emerging role in adoptive cellular immunotherapy
MedComm, 2021 Adoptive cellular immunotherapy harnessing the intrinsic immune system for precise treatment has exhibited preliminary success against malignant tumors.
Yicheng Zhu +4 more
doaj +1 more source
Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model. [PDF]
PLoS ONE, 2015 Adoptive transfer of gene modified T cells provides possible immunotherapy for patients with cancers refractory to other treatments. We have previously used the non-viral piggyBac transposon system to gene modify human T cells for potential immunotherapy.
Daniel L Galvan +6 more
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A novel and effective cancer immunotherapy mouse model using antigen-specific B cells selected in vitro. [PDF]
PLoS ONE, 2014 Immunotherapies such as adoptive transfer of T cells or natural killer cells, or monoclonal antibody (MoAb) treatment have recently been recognized as effective means to treat cancer patients.
Tatsuya Moutai +3 more
doaj +1 more source
Hematology, Transfusion and Cell Therapy, 2021 The use of immunotherapy in cancer treatment over the past decade has resulted in significant advances and improvements in cancer patients survival with the use of checkpoint inhibitors.
Mirella Nardo +3 more
doaj +1 more source
Frontiers in Pharmacology, 2021 So far, immunotherapy has been shown to have impressive effects on different cancers in clinical trials. All those immunotherapies are generally derived from three main therapeutic approaches: immune checkpoint inhibitors, immune cell vaccination, and ...
Fanming Kong +7 more
doaj +1 more source
Efficiency of ADOPTIVE immunotherapy for melanoma: a case REPORT
Сибирский онкологический журнал, 2016 A lot of research is focused on finding better treatment options for cancer. Along with radical treatment, cancer immunotherapy has proved to be useful for a growing number of cancer patients.
E. V. Abakushina +5 more
doaj +1 more source
LYMPHOCYTE PHENOTYPE IN PATIENTS WITH SKIN MELANOMA AFTER IMMUNOTHERAPY OF ACTIVATED LYMPHOCYTES
Медицинская иммунология, 2015 The major medical problem in the treatment of skin melanoma is improvement methods of treatment, increasing their effectiveness and safety. In this study, adoptive immunotherapy, using lymphocytes activated in vitro, was performed in 15 patients with ...
E. V. Abakushina +5 more
doaj +1 more source