Results 1 to 10 of about 368,892 (303)

Promises and Pitfalls of Next-Generation Treg Adoptive Immunotherapy. [PDF]

Cancers (Basel), 2023
Simple Summary Adoptive immunotherapy has emerged as an effective alternative of mounting impact to the current standard of care in cancer, viral infections, and recently, autoimmunity.
Christofi P, Pantazi C, Psatha N, Sakellari I, Yannaki E, Papadopoulou A.   +5 more
europepmc   +2 more sources

Natural killer cells in antitumour adoptive cell immunotherapy

Nature Reviews Cancer, 2022
Natural killer (NK) cells comprise a unique population of innate lymphoid cells endowed with intrinsic abilities to identify and eliminate virally infected cells and tumour cells.
Katy Rezvani, Alexander Biederstädt, Rezvani Katayoun   +2 more
exaly   +2 more sources

TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer. [PDF]

Cell Rep Med, 2021
Summary Despite its role in cancer surveillance, adoptive immunotherapy using γδ T cells has achieved limited efficacy. To enhance trafficking to bone marrow, circulating Vγ9Vδ2 T cells are expanded in serum-free medium containing TGF-β1 and IL-2 (γδ[T2]
Beatson RE, Parente-Pereira AC, Halim L, Cozzetto D, Hull C, Whilding LM, Martinez O, Taylor CA, Obajdin J, Luu Hoang KN, Draper B, Iqbal A, Hardiman T, Zabinski T, Man F, de Rosales RTM, Xie J, Aswad F, Achkova D, Joseph CR, Ciprut S, Adami A, Roider HG, Hess-Stumpp H, Győrffy B, Quist J, Grigoriadis A, Sommer A, Tutt ANJ, Davies DM, Maher J.   +30 more
europepmc   +2 more sources

Adoptive Immunotherapy beyond CAR T-Cells. [PDF]

Cancers (Basel), 2021
Simple Summary The aging of the world population leads to a constant increase of cancer-related morbidity and mortality. Treatment of late-stage tumors has become a significant burden on the healthcare system globally.
Titov A, Zmievskaya E, Ganeeva I, Valiullina A, Petukhov A, Rakhmatullina A, Miftakhova R, Fainshtein M, Rizvanov A, Bulatov E.   +9 more
europepmc   +2 more sources

Adoptive Immunotherapy for Cancer or Viruses [PDF]

Annual Review of Immunology, 2014
Adoptive immunotherapy, or the infusion of lymphocytes, is a promising approach for the treatment of cancer and certain chronic viral infections. The application of the principles of synthetic biology to enhance T cell function has resulted in substantial increases in clinical efficacy.
Bruce Levine, Joseph Fraietta, Marcela Maus   +2 more
exaly   +3 more sources

Adoptive Immunotherapy

Methods in Molecular Medicine™, 2004
INSTRUCTIONS FOR USE The following Coverage Policy applies to health benefit plans administered by Cigna Companies. Certain Cigna Companies and/or lines of business only provide utilization review services to clients and do not make coverage ...
Burkhard Ludewig, Matthias W. Hoffmann
openaire   +2 more sources

The Emerging Role of In Vitro-Transcribed mRNA in Adoptive T Cell Immunotherapy

Molecular Therapy, 2019
Adoptive T cell therapy is a form of cellular therapy that utilizes human immune cells, often empowered by the expression of recombinant proteins, to attack selected targets present on tumor or infected cells.
Katalin Kariko, Jessica Foster, David Barrett   +2 more
exaly   +2 more sources

Adoptive T Cell Immunotherapy for Cancer [PDF]

Rambam Maimonides Medical Journal, 2015
Harnessing the immune system to recognize and destroy tumor cells has been the central goal of anti-cancer immunotherapy. In recent years, there has been an increased interest in optimizing this technology in order to make it a clinically feasible ...
Karlo Perica, Juan Carlos Varela, Mathias Oelke, Jonathan Schneck   +3 more
doaj   +3 more sources

Genetically Modified T-Cell-Based Adoptive Immunotherapy in Hematological Malignancies

Journal of Immunology Research, 2017
A significant proportion of hematological malignancies remain limited in treatment options. Immune system modulation serves as a promising therapeutic approach to eliminate malignant cells.
Baixin Ye, Creed M. Stary, Qingping Gao, Qiongyu Wang, Zhi Zeng, Zhihong Jian, Lijuan Gu, Xiaoxing Xiong   +7 more
doaj   +2 more sources

Pre-emptive and therapeutic adoptive immunotherapy for nasopharyngeal carcinoma: Phenotype and effector function of T cells impact on clinical response

OncoImmunology, 2017
Adoptive T cell therapy has emerged as a powerful strategy to treat human cancers especially haematological malignancies. Extension of these therapies to solid cancers remains a significant challenge especially in the context of defining immunological ...
Corey Smith, Victor Lee, Andrea Schuessler, Leone Beagley, Sweera Rehan, Janice Tsang, Vivian Li, Randal Tiu, David Smith, Michelle A. Neller, Katherine K. Matthews, Emma Gostick, David A. Price, Jacqueline Burrows, Glen M. Boyle, Daniel Chua, Benedict Panizza, Sandro V. Porceddu, John Nicholls, Dora Kwong, Rajiv Khanna   +20 more
doaj   +2 more sources