Results 11 to 20 of about 214,380 (250)

Adoptive immunotherapy for cytomegalovirus infection

Journal of Applied Sciences and Environmental Management, 2005
We reported a case with interstitial pneumonia associated with cytomegalovirus (CMV) infection in whom clinical improvement was observed after the treatment with primary adoptive immunotherapy.
M D Kei Numazaki
doaj   +2 more sources

Promises and Pitfalls of Next-Generation Treg Adoptive Immunotherapy. [PDF]

Cancers (Basel), 2023
Regulatory T cells (Tregs) are fundamental to maintaining immune homeostasis by inhibiting immune responses to self-antigens and preventing the excessive activation of the immune system.
Christofi P, Pantazi C, Psatha N, Sakellari I, Yannaki E, Papadopoulou A.   +5 more
europepmc   +2 more sources

Adoptive Immunotherapy and High-Risk Myeloma. [PDF]

Cancers (Basel), 2023
Despite significant improvements in the treatment of multiple myeloma (MM), it remains mostly incurable, highlighting a need for new therapeutic approaches.
Duane C, O'Dwyer M, Glavey S.
europepmc   +2 more sources

In vivo application of recombinant interleukin 2 in the immunotherapy of established cytomegalovirus infection [PDF]

, 1987
We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that in vivo application of recombinant human IL-2 (rhIL-2) can enhance the antiviral effect of a limited number of CD8+T lymphocytes, not only in ...
Reddehase, Matthias J., W Mutter, Koszinowski, Ulrich H., Wolfgang Mutter, J. Reddehase, M J Reddehase, U H Koszinowski, Koszinowski, Ulrich, Mutter, Wolfgang, Ulrich H. Koszinowski   +9 more
core   +2 more sources

Antibodies Are Not Essential for the Resolution of Primary Cytomegalovirus Infection but Limit Dissemination of Recurrent Virus [PDF]

, 1994
Virus shedding from the epithelial cells of the serous acini of salivary glands is a major source for the horizontal transmission of cytomegalovirus. These cells are, different to other tissues, exempt from CD8 T lymphocyte control. CD4 T lymphocytes are
Crnkovic, Irena, Pavic, Ivica, Koszinowski, Ulrich H., Lucin, Pero, Polic, Bojan, Jonjic, Stipan   +5 more
core   +2 more sources

Immunotherapy of lung cancer: An update [PDF]

, 2006
In Germany lung cancer is the leading cause of cancer-associated death in men. Surgery, chemotherapy and radiation may enhance survival of patients suffering from lung cancer but the enhancement is typically transient and mostly absent with advanced ...
Hatz, R. A., Jauch, Karl-Walter, van den Engel, N.K., Fox, B.A., Grützner, S., Hatz, R.A., Rüttinger, D., Fox, B. A., Jauch, K.-W., Winter, H., van den Engel, N. K., Schendel, D. J., Pohlac, H., Pohla, H., Schlemmer, M., Schendel, D.J.   +15 more
core   +1 more source

Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]

, 2003
Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to ...
Kolb, Hans-Jochem, Roskrow, Marie, Guenther, Wolfgang, Schmid, Christoph, Ledderose, Georg, Weber, Martin, Chen, Xiao, Schleuning, Michael, Woiciechowski, Anja   +8 more
core   +1 more source

T-Cell Dysfunction as a Limitation of Adoptive Immunotherapy: Current Concepts and Mitigation Strategies

, 2021
Over the last decades, cellular immunotherapy has revealed its curative potential. However, inherent physiological characteristics of immune cells can limit the potency of this approach.
Jean-Sébastien Delisle, Valérie Janelle   +1 more
core   +1 more source

TCR Gene Therapy: Challenges, Opportunities, and Future Directions

Cells, 2020
Adoptive immunotherapy with gene-engineered T cells has provided new treatment options for cancer patients [...]
Hans J. Stauss, Maxine G. B. Tran
doaj   +1 more source

An escherichia coli vaccine co-expressing listeriolysin-O and tumour antigen in cancer immunotherapy and the mechanisms of immune regulation [PDF]

, 2009
PhDSome recombinant bacterial strains have been shown to be very efficient in experimental therapies against cancer in rodent models. Amongst them is an E. coli that expresses the Listeriolysin-O protein (LLO) and a model tumour antigen ovalbumin (OVA)
Dai, Ming-Shen
core   +4 more sources