Results 21 to 30 of about 214,380 (250)

Adoptive Natural Killer Cell Immunotherapy for Canine Osteosarcoma

Frontiers in Veterinary Science, 2021
Osteosarcoma is the most common primary bone tumor in both humans and dogs. It is a highly metastatic cancer and therapy has not improved significantly since the inclusion of adjuvant chemotherapy into disease treatment strategies.
William C. Kisseberth, Dean A. Lee
doaj   +1 more source

Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy. [PDF]

, 2007
Epstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive transfer ...
Burdach, S., Witter, K., Boerschmann Heike, Boerschmann, H., Mautner, Josef, Georg W Bornkamm, Adhikary, D., Adhikary, Dinesh, Uta Behrends, Burdach Stefan, Bornkamm, G.W., Mautner, J., Georg W, Andrea Pfünder, Moosmann, A., Witter Klaus, Adhikary Dinesh, Pfünder, Andrea, Dinesh Adhikary, Klaus Witter, Pfünder Andrea, Josef Mautner, Behrends Uta, Stefan Burdach, Moosmann Andreas, Andreas Moosmann, Bornkamm Georg W., Behrends, Uta, Boerschmann, Heike, Burdach, Stefan, Bornkamm, Georg W., Pfünder, A., Witter, Klaus, Behrends, U., Mautner Josef, Moosmann, Andreas, Heike Boerschmann   +36 more
core   +1 more source

Human CAR NK Cells: A New Non-viral Method Allowing High Efficient Transfection and Strong Tumor Cell Killing

Frontiers in Immunology, 2019
CAR-NK cells may represent a valuable tool, complementary to CAR-T cells, in adoptive immunotherapy of leukemia and solid tumors. However, gene transfer to human NK cells is a challenging task, particularly with non-virus-based techniques.
Tiziano Ingegnere, Francesca Romana Mariotti, Andrea Pelosi, Concetta Quintarelli, Concetta Quintarelli, Biagio De Angelis, Nicola Tumino, Francesca Besi, Claudia Cantoni, Franco Locatelli, Paola Vacca, Lorenzo Moretta   +11 more
doaj   +1 more source

Combined therapy with cytokine-induced killer cells and oncolytic adenovirus expressing IL-12 induce enhanced antitumor activity in liver tumor model. [PDF]

PLoS ONE, 2012
Both adoptive immunotherapy and gene therapy hold a great promise for treatment of malignancies. However, these strategies exhibit limited anti-tumor activity, when they are used alone.
Zhi Yang, Qianzhen Zhang, Ke Xu, Juanjuan Shan, Junjie Shen, Limei Liu, Yanmin Xu, Feng Xia, Ping Bie, Xia Zhang, Youhong Cui, Xiu-Wu Bian, Cheng Qian   +12 more
doaj   +1 more source

Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy

eLife, 2016
The combined-immunotherapy of adoptive cell therapy (ACT) and cyclophosphamide (CTX) is one of the most efficient treatments for melanoma patients. However, no synergistic effects of CTX and ACT on the spatio-temporal dynamics of immunocytes in vivo have
Shuhong Qi, Hui Li, Lisen Lu, Zhongyang Qi, Lei Liu, Lu Chen, Guanxin Shen, Ling Fu, Qingming Luo, Zhihong Zhang   +9 more
doaj   +1 more source

Adoptive immunotherapy for cytomegalovirus infection [PDF]

, 2004
We reported a case with interstitial pneumonia associated with cytomegalovirus (CMV) infection in whom clinical improvement was observed after the treatment with primary adoptive immunotherapy.
Kei Numazaki
core   +3 more sources

The Application of iPSCs in Tumour Immunotherapy

Expert Reviews in Molecular Medicine
Background Tumour immunotherapy holds great promise as a treatment for cancer, which ranks as the second highest cause of mortality worldwide. This therapeutic approach can be broadly categorized into two main types: active immunotherapy and passive or ...
Peinan Chen, Jian Gao, Jianing Feng, Hongfei Tao, Yongkui Yu, Yijing Li, Jinlong Liu, Shuangshuang Lu, Wei Wang   +8 more
doaj   +1 more source

A 9L Gliosarcoma Transplantation Model for Studying Adoptive Immunotherapy into the Brains of Conscious Rats

Cell Transplantation, 1992
A rat model for brain tumor immunotherapy is described that closely mimics the type of treatment that could be administered to humans. It involves surgical implantation of a permanent cannula in the brain, through which tumor cells and various effector ...
Monika Fleshner, Linda R. Watkins, Joan M. Redd, Carol A Kruse, Donald Bellgrau   +4 more
doaj   +1 more source

The State of Cellular Adoptive Immunotherapy for Neuroblastoma and Other Pediatric Solid Tumors

Frontiers in Immunology, 2017
Research on adult cancer immunotherapy is proceeding at a rapid pace resulting in an impressive success rate exemplified by a few high profile cases. However, this momentum is not readily extended to pediatric immunotherapy, and it is not for lack of ...
Thanh-Phuong Le, To-Ha Thai
doaj   +1 more source

Application of Immunotherapy in Hepatocellular Carcinoma

Frontiers in Oncology, 2021
Hepatocellular carcinoma is one of the most common malignancies globally. It not only has a hidden onset but also progresses rapidly. Most HCC patients are already in the advanced stage of cancer when they are diagnosed, and have even lost the ...
Lele Miao, Lele Miao, Zhengchao Zhang, Zhengchao Zhang, Zhijian Ren, Zhijian Ren, Yumin Li, Yumin Li   +7 more
doaj   +1 more source