Results 31 to 40 of about 2,335,939 (309)
Determination of Cellular Uptake and Endocytic Pathways
Efficiency of drug and gene delivery via nonviral vehicles is contingent on proper cellular uptake and intracellular release. Further, various cargos, such as nucleases for gene editing or inhibitors for endosomal receptors, require transport to specific
Jing Gong, Hong-Xia Wang, Kam Leong
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Cellular Ingestible DNA Nanostructures for Biomedical Applications
Delivering functional substances across the cell membrane barriers has been a great challenge in biomedicine. Among various strategies to improve cellular uptake, DNA nanostructures, with different shapes and sizes, supply as suitable platforms for ...
Rui Xu +4 more
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Growing gold nanostructures for shape-selective cellular uptake
With development in the synthesis of shape- and size-dependent gold (Au) nanostructures (NSs) and their applications in nanomedicine, one of the biggest challenges is to understand the interaction of these shapes with cancer cells.
Sulalit Bandyopadhyay +7 more
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Small interfering RNAs (siRNAs) have potential to silence virtually any disease-causing gene but require chemical modifications for delivery to the tissue and cell of interest.
Socheata Ly +3 more
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Amino acid uptake in Arabidopsis [PDF]
Nitrogen (N) is essential for all living organisms and is considered to be the limiting factor for plant growth in many ecosystems. Although generally believed to rely on mineral N to fulfill their N needs, plants have also been found to access organic N
Svennerstam, Henrik
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Cell Type-Specific Modulation of Cobalamin Uptake by Bovine Serum.
Tracking cellular 57Co-labelled cobalamin (57Co-Cbl) uptake is a well-established method for studying Cbl homeostasis. Previous studies established that bovine serum is not generally permissive for cellular Cbl uptake when used as a supplement in cell ...
Hua Zhao +3 more
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Controlling the Cellular Uptake of Gold Nanorods [PDF]
Gold nanorods coated with cetyltrimethylammonium bromide (CTAB), a cationic micellar surfactant used in nanorod synthesis, were rapidly and irreversibly internalized by KB cells via a nonspecific uptake mechanism. Internalized nanorods near the cell surface were monitored by two-photon luminescence (TPL) microscopy and observed to migrate toward the ...
Terry B, Huff +4 more
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Entropy‐Mediated Nanoparticle Cellular Uptake
Entropy, as one of the key parameters defining thermodynamic systems, is extensively explored in various scientific fields covering physics, chemistry, biology, etc. Particularly, understanding the entropic effects in cellular uptake is critical to understanding how physicochemical interactions govern the structure, response, and function of biological
Haixiao Wan +3 more
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Vitamin E is classified into tocopherol (Toc) and tocotrienol (T3) based on its side chains. T3 generally has higher cellular uptake than Toc, though the responsible mechanism remains unclear. To elucidate this mechanism, we hypothesized and investigated
Takashi Nakatomi +10 more
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ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source

