Results 61 to 70 of about 1,858 (240)

A brief review on new naturally occurring cembranoid diterpene derivatives from the soft corals of the genera Sarcophyton, Sinularia, and Lobophytum since 2016 [PDF]

open access: yes, 2019
This work reviews the new isolated cembranoid derivatives from species of the genera Sarcophyton, Sinularia, and Lobophytum as well as their biological properties, during 2016⁻2018.
Miguel, Maria   +2 more
core   +1 more source

A Great Barrier Reef <em>Sinularia</em> sp. Yields Two New Cytotoxic Diterpenes

open access: yesMarine Drugs, 2012
The methanol extract of a <em>Sinularia </em>sp., collected from Bowden Reef, Queensland, Australia, yielded ten natural products. These included the new nitrogenous diterpene (4<em>R</em>*,5<em>R</em>*,9<em>S<
Cherie A. Motti   +4 more
doaj   +1 more source

An Unexpected Transannular [4+2] Cycloaddition during the Total Synthesis of (+)‐Norcembrene 5

open access: yesAngewandte Chemie International Edition, Volume 59, Issue 14, Page 5521-5525, March 27, 2020., 2020
They may look alike… During studies toward the total synthesis of the norditerpene natural product norcembrene 5, one diastereomer of a key intermediate (α‐OAc at C13) underwent clean and spontaneous Diels–Alder cycloaddition at room temperature (see scheme).
Michael Breunig, Po Yuan, Tanja Gaich
wiley   +1 more source

New Cembranoid Diterpenes from the Cultured Octocoral Nephthea columnaris

open access: yesMolecules, 2015
Two new 15-hydroxycembranoid diterpenes, 2β-hydroxy-7β,8α-epoxynephthenol (1) and 2β-hydroxy-11α,12β-epoxynephthenol (2), were isolated from extracts of the octocoral Nephthea columnaris along with a new natural cembrane, epoxynephthenol (3) and a known ...
Ting-Hsi Hsiao   +8 more
doaj   +1 more source

EBC‐342: A Novel Tetrahydrofuran Moiety Containing Casbane from the Australian Rainforest

open access: yesEuropean Journal of Organic Chemistry, Volume 2020, Issue 8, Page 1042-1045, February 28, 2020., 2020
Although well known, the casbane family of natural products are not often isolated from either terrestrial or marine environments. The Australian Rainforest plant Croton insularis has provided a number of interesting casbanes, of which EBC‐342 described herein, is the first to contain a tetrahydrofuran ring.
Lidia A. Maslovskaya   +9 more
wiley   +1 more source

Terpenoids from Octocorals of the Genus Pachyclavularia

open access: yesMarine Drugs, 2017
In this paper, we reviewed natural compounds isolated from octocorals belonging to the genus Pachyclavularia, including 20 cembrane-, 39 briarane-, and eight briarellin-related diterpenoids, and one secosterol.
Yu-Chia Chang   +3 more
doaj   +1 more source

Four Phragmalin Orthoesters from the Chinese Mangrove Xylocarpus granatum [PDF]

open access: yes, 2018
K
Gu, Yu-Cheng   +7 more
core   +1 more source

Neuroactive and Anti-inflammatory Frankincense Cembranes: A Structure–Activity Study [PDF]

open access: yesJournal of Natural Products, 2016
An expeditious isolation method for the cembrane diterpene alcohols incensol (1a) and serratol (2) has been developed from respectively African and Indian frankincense. The two native alcohols and a series of semisynthetic derivatives of incensol were evaluated for transient receptor potential vanilloid 3 (TRPV3) activation and the inhibition of NF-κB,
Pollastro, Federica   +9 more
openaire   +5 more sources

The evolution of genome mining in microbes – a review [PDF]

open access: yes, 2016
This article reviews the development of genome mining strategies in bacteria during the last decade.
Alanjary, Mohammad   +2 more
core   +1 more source

A High-Content Screening Assay for the Discovery of Novel Proteasome Inhibitors from Formosan Soft Corals

open access: yesMarine Drugs, 2018
The ubiquitin-proteasome system (UPS) is a major proteolytic pathway that safeguards protein homeostasis. The main 26S proteasome consists of a 20S catalytic core proteasome and a 19S substrate recognition proteasome.
Xue-Hua Ling   +4 more
doaj   +1 more source

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