Results 71 to 80 of about 1,077 (172)

Immunomodulatory Effect of Marine Cembrane-Type Diterpenoids on Dendritic Cells

Marine Drugs, 2013
Dendritic cells (DCs) are antigen presenting cells, which can present antigens to T-cells and play an important role in linking innate and adaptive immunity. DC maturation can be induced by many stimuli, including pro-inflammatory cytokines and bacterial
Kao-Jean Huang, Ping-Jyun Sung, Ching-Feng Weng, Jui-Hsin Su, Ching-Liang Chu, David Shiuan, Mei-Chin Lu, Ching-Yen Lin   +7 more
doaj   +1 more source

Potent pigmentation inhibitory activity of incensole‐enriched frankincense volatile oil‐identification, efficacy and mechanism

Journal of Cosmetic Dermatology, Volume 23, Issue 1, Page 244-255, January 2024.
Abstract Background Frankincense volatile oil (FVO) has long been considered a side product in pharmaceutical industry since frankincense of large molecular weight is the prime target. However, the volatile oil recycled in the extract process might contain a series of functional actives, serving as promising ingredients in the cosmetic field.
Xiufang Yan, Xiaoyu Ma, Daoxin Dai, Xiaojuan Yan, Xingyan Han, Xijun Bao, Qiufang Xie   +6 more
wiley   +1 more source

Cembranoids from a Chinese Collection of the Soft Coral Lobophytum crassum

Marine Drugs, 2016
Ten new cembrane-based diterpenes, locrassumins A–G (1–7), (–)-laevigatol B (8), (–)-isosarcophine (9), and (–)-7R,8S-dihydroxydeepoxysarcophytoxide (10), were isolated from a South China Sea collection of the soft coral Lobophytum crassum, together with
Min Zhao, Shimiao Cheng, Weiping Yuan, Yiyuan Xi, Xiubao Li, Jianyong Dong, Kexin Huang, Kirk R. Gustafson, Pengcheng Yan   +8 more
doaj   +1 more source

A soft coral-derived compound, 11-epi-sinulariolide acetate suppresses inflammatory response and bone destruction in adjuvant-induced arthritis. [PDF]

PLoS ONE, 2013
In recent years, a significant number of metabolites with potent anti-inflammatory properties have been discovered from marine organisms, and several of these compounds are now under clinical trials. In the present study, we isolated 11-epi-sinulariolide
Yen-You Lin, Yen-Hsuan Jean, Hsin-Pai Lee, Wu-Fu Chen, Yu-Min Sun, Jui-Hsin Su, Yi Lu, Shi-Ying Huang, Han-Chun Hung, Ping-Jyun Sung, Jyh-Horng Sheu, Zhi-Hong Wen   +11 more
doaj   +1 more source

Aquaculture Soft Coral Lobophytum crassum as a Producer of Anti-Proliferative Cembranoids

Marine Drugs, 2018
Our continuous search for marine bioactive secondary metabolites led to the screening of crude extracts from a variety of aquaculture soft corals. The ethyl acetate (EtOAc) extract of Lobophytum crassum showed a distinctive chemical profile that was ...
Bo-Rong Peng, Mei-Chin Lu, Mohamed El-Shazly, Shwu-Li Wu, Kuei-Hung Lai, Jui-Hsin Su   +5 more
doaj   +1 more source

Characterization of Volatile Organic Compounds and Aroma Sensory Properties in Yunnan Cigar

Journal of Analytical Methods in Chemistry, Volume 2024, Issue 1, 2024.
To characterize volatile organic compounds (VOCs) and aromatic sensory properties in Yun cigar, 27 samples from four origins were analyzed using SPME–HS–GC/MS and sensory analysis. The investigation results were analyzed using principal component analysis (PCA), Fisher linear discriminant analysis (LDA), and Pearson correlation analysis.
Yuping Wu, Haiyu Zhang, Wenyuan Wang, Guanghui Kong, Zaiming Li, Tikun Zhang, Miaochang Wang, Dong Yang, Chengming Zhang, Yongping Li, Jin Wang, Serban Moldoveanu   +11 more
wiley   +1 more source

Interaction of α‐Cembrenediol with Human Serum Albumin Based on Spectroscopic and Computational Analyses

Journal of Spectroscopy, Volume 2024, Issue 1, 2024.
α‐Cembrenediol exhibits a wide range of biological activities, including antibacterial, antitumor, and neuroprotective effects. However, knowledge of the absorption, transport, and release of α‐cembrenediol in drug metabolism within the body is currently limited.
Xian-Kun Su, Zhen-Chun Sun, Chang-You Zhao, Hui Yang, Tian-Ming Zhao, Chao Ma, Guo-Fei Zhu, Mohd Sajid Ali   +7 more
wiley   +1 more source

Genotoxicity and 28-day repeated dose oral toxicity study of ovatodiolide in rats

Toxicology Reports, 2021
Ovatodiolide is a bioactive cembrane-type diterpenoid isolated from Anisomeles indica (L.) Kuntze. It has been proven that ovatodiolide is anti-inflammatory, anti-tumorigenic, anti-melanogenic and attenuates asthma by regulating signaling pathways.
Jing-Chun Chen, Yan-Zhen Dai, Yew-Min Tzeng, Jiunn-Wang Liao   +3 more
doaj   +1 more source

Isolation and Structure Elucidation of Cembranoids from a Dongsha Atoll Soft Coral Sarcophyton stellatum

Marine Drugs, 2018
Six new polyoxygenated cembrane-based diterpenoids, stellatumolides A–C (1–3), stellatumonins A and B (4 and 5), and stellatumonone (6), were isolated together with ten known related compounds (7–16) from the ethyl acetate (EtOAc ...
Atallah F. Ahmed, Yi-Wei Chen, Chiung-Yao Huang, Yen-Ju Tseng, Chi-Chen Lin, Chang-Feng Dai, Yang-Chang Wu, Jyh-Horng Sheu   +7 more
doaj   +1 more source

New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp.

Marine Drugs, 2012
Five new cembrane diterpenoids, named sinuflexibilins A–E (1–5), along with nine other known diterpenoids (6–14), have been isolated from the organic extract of a Hainan soft coral Sinularia sp. Their structures were determined on the basis of extensive spectroscopic analyses and by comparison of their spectral data with those of related metabolites ...
Bin Yang, Xuefeng Zhou, Hui Huang, Xian-Wen Yang, Juan Liu, Xiuping Lin, Xiubao Li, Yan Peng, Yonghong Liu   +8 more
openaire   +2 more sources