Synthetic Study of Sarcophytol A, an Anticarcinogenic Cembranoid.
The first total synthesis of sarcophytol A, an anticarcinogenic marine cembranoid, was achieved in a highly stereo- and enantioselective manner starting with (E, E)-farnesol ; it includes : 1) a newly developed Z-selective (Z : E=>35 : 1) Horner-Emmons reaction using a phosphonate nitrile, 2) a modified cyanohydrin macrocyclization, and 3) an ...
openaire +2 more sources
Three new diterpenes from a soft coral Nephthea species [PDF]
Two new cembranoid diterpenes and a non-cembranoid diterpene have been isolated from a soft coral Nephthea species along with two previously reported diterpenes (1) and (9).
SE Poet, BN Ravi
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Lobophytones A−G, New Isobiscembranoids from the Soft Coral Lobophytum pauciflorum [PDF]
Seven new biscembranoids, lobophytones A−G (1−7), together with three known biscembranes were isolated from the Chinese soft coral Lobophytum pauciflorum.
Leen van Ofwegen (1906201) +4 more
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Feasibility of metabolomic analysis in assessing coral reefs environments.
This study aimed to explain the feasibility of fingerprint and chemical marker metabolomicanalysis in assessment of coral reefs environments. Based on literature review, both analysismight be implemented on coral reef environment assessment, with their ...
Hedi Indra Januar +2 more
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Synthesis and stereochemistry of sarcophytol B: An anticancer cembranoid
Abstract A short (5 step), efficient synthesis of sarcophytol B (1) from farnesal is reported using a low-temperature, titanium-induced pinacol coupling reaction of 1,14-dialdehyde5 as the key step. An X-ray structure determination showed that sarcophytol B has trans diol stereochemistry.
John E. McMurry +2 more
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Based on metabolomics, the optimum wind speed process parameters of flue-cured tobacco in heat pump bulk curing barn were explored. [PDF]
Sun CL +6 more
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Investigation and total assignment of the 13C-NMR spectra of the cembranoid diterpenes sinularin, dihydrosinularin, eunicin and jeunicin [PDF]
Marine invertebrates of the phylum Coelenterata have been found to contain a variety of cembranoid diterpenes of chemical, biological and spectroscopic interest. The cembranes selected for this study include sinularin and di hydrosinularin extracted from
Gampe, Robert T., Jr.
core
Asymmetric Total Synthesis of Havellockate. [PDF]
Hafeman NJ +6 more
europepmc +1 more source
The Soft Coral Sarcophyton trocheliophorum: A Warehouse of Terpenoids with Structural and Pharmacological Diversity. [PDF]
Yang QB, Wu Q, Chen JK, Liang LF.
europepmc +1 more source
Total Synthesis of Rameswaralide Utilizing a Pharmacophore-Directed Retrosynthetic Strategy. [PDF]
Truax NJ, Ayinde S, Liu JO, Romo D.
europepmc +1 more source

