Extracellular Vesicles from Compression‐Loaded Cementoblasts Promote the Tissue Repair Function of Macrophages [PDF]
Advanced ScienceTreatment strategies for hard tissue defects aim to establish a mineralized microenvironment that facilitates tissue remodeling. As a mineralized tissue, cementum shares a similar structure with bone and exhibits an excellent capacity to resist ...
Yuhui Yang +7 more
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Orthodontic tension promotes cementoblast mineralization by regulating autophagy [PDF]
Journal of Dental SciencesBackground/purpose: External root resorption is a main side effect of orthodontic treatment and is more likely to occur on the pression side than the tension side.
Yi Zhao +5 more
doaj +5 more sources
Resveratrol modulates phosphorylation of ERK and AKT in murine cementoblasts during in vitro orthodontic compression [PDF]
BMC Oral HealthObjective Resveratrol is a plant polyphenol known for its anti-inflammatory and pro-regenerative properties. These could be beneficial in controlling potential side effects of orthodontic treatment, such as apical root resorption.
Shams Negm +10 more
doaj +4 more sources
Mitochondrial ROS participates in Porphyromonas gingivalis-induced pyroptosis in cementoblasts [PDF]
Heliyon, 2023 This study aimed to investigate correlation between mitochondrial reactive oxygen species and Porphyromonas gingivalis in the process of cementoblast pyroptosis.
Weiman Sun +4 more
doaj +5 more sources
Comparison of different graft materials on the proliferation, mineralization and mineralized tissue-related gene expressions of cementoblasts [PDF]
Journal of Materials Science: Materials in MedicineCementoblasts and formation of new cementum are crucial for periodontal regeneration. The aim of this study is to investigate the effect of different graft materials on cementoblast’s proliferation, mineralization and mineralized tissue-related gene ...
E. Elif Mutafcilar Velioğlu +3 more
doaj +3 more sources
Immunorthodontics: PD-L1, a Novel Immunomodulator in Cementoblasts, Is Regulated by HIF-1α under Hypoxia [PDF]
Cells, 2022 Recent studies have revealed that hypoxia alters the PD-L1 expression in periodontal cells. HIF-1α is a key regulator for PD-L1. As hypoxia presents a hallmark of an orthodontically induced microenvironment, hypoxic stimulation of PD-L1 expression may ...
Jiawen Yong +4 more
doaj +3 more sources
HK2-mediated Glycolysis Inhibits Mineralization of Cementoblasts Under Compression by Suppressing the Piezo1/Wnt Signaling. [PDF]
Int J Med SciBackground: Orthodontically induced inflammatory root resorption (OIIRR) is a prevalent and severe complication during orthodontic tooth movement (OTM). Glycolysis plays a crucial role in the inflammatory responses.
Huang Z, Hu H, Meng Y, Li H, Lei L.
europepmc +4 more sources
Xanthohumol exerts anti-inflammatory effects in an in vitro model of mechanically stimulated cementoblasts [PDF]
Scientific Reports, 2022 Xanthohumol (XN) is a prenylated plant polyphenol that naturally occurs in hops and its products, e.g. beer. It has shown to have anti-inflammatory and angiogenesis inhibiting effects and it prevents the proliferation of cancer cells. These effects could
Christian Niederau +5 more
doaj +3 more sources
Triethylene-glycol-dimethacrylate induces caspase-mediated apoptotic cell death in cementoblasts by the regulation of JNK and p38 pathways-an in vitro study. [PDF]
J Dent SciLai WJ +4 more
europepmc +3 more sources
Correction to "Extracellular Vesicles from Compression-Loaded Cementoblasts Promote the Tissue Repair Function of Macrophages". [PDF]
Adv Sci (Weinh)europepmc +4 more sources