Recombinant amelogenin regulates the bioactivity of mouse cementoblasts in vitro [PDF]
International Journal of Oral Science, 2018 Regenerative medicine: Engineered amelogenin boosts oral cell activity A protein with its roots in dental development stimulates the proliferation and gene expression of cells linked to regeneration.
Sema S. Hakki +5 more
doaj +6 more sources
Restoration of Cementoblast Mineralization by Glutamine Under Inflammatory Conditions [PDF]
International Dental Journal: Introduction and Aims: Cementoblasts are critical for cementum formation and periodontal regeneration during inflammatory diseases such as periodontitis and apical periodontitis (AP). Bacterial infection leads to metabolic changes in cementoblasts and
Mengjie Yin +10 more
doaj +2 more sources
Hypoxia‐inducible factor 1‐alpha acts as a bridge factor for crosstalk between ERK1/2 and caspases in hypoxia‐induced apoptosis of cementoblasts [PDF]
Journal of Cellular and Molecular Medicine, 2021 Hypoxia‐induced apoptosis of cementoblasts (OCCM‐30) may be harmful to orthodontic treatment. Hypoxia‐inducible factor 1‐alpha (HIF‐1α) mediates the biological effects during hypoxia.
Jiawen Yong +4 more
semanticscholar +2 more sources
Caspase activation by a zinc-oxide eugenol-based root-canal sealer in cementoblasts
Journal of Dental Sciences, 2015 The purpose of this study was to determine the cytotoxicity of the zinc-oxide eugenol-based root-canal sealer Canals on murine immortalized cementoblast cell line.
Fu-Mei Huang +3 more
doaj +2 more sources
Deficiency of Trps1 in Cementoblasts Impairs Cementogenesis and Tooth Root Formation. [PDF]
Calcif Tissue IntCementum is the least studied of all mineralized tissues and little is known about mechanisms regulating its formation. Therefore, the goal of this study was to provide new insights into the transcriptional regulation of cementum formation by determining
Fujikawa K +6 more
europepmc +2 more sources
Development, Establishment, and Validation of a Model for the Mineralization of Periodontium Remodelling Cells: Cementoblasts. [PDF]
Int J Mol Sci, 2023 Chronic kidney disease (CKD) patients undergoing dialysis are at high risk of bone fractures. CKD-induced mineral and bone disorder is extended to periodontal disease due to changes in the ionic composition of saliva in CKD patients, dysregulating ...
Bhargava S +5 more
europepmc +2 more sources
Frontiers in Physiology, 2022 Cementum resorption, unlike bone resorption, is clinically known to occur only with limited pathological stimuli, such as trauma, orthodontic forces, and large apical periodontitis; however, the molecular mechanisms that control osteoclast formation on ...
Rei Sato +8 more
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Conditioned medium from cultured cementoblasts upregulates amelotin gene expression via the SOCS3 signaling pathway. [PDF]
J Periodontal Implant SciPurpose The junctional epithelium (JE) covers the cervical areas of developing or existing teeth. It can re-establish itself even after being removed during periodontal therapies, followed by wound healing.
Nakayama Y +5 more
europepmc +2 more sources
Frontiers in Bioscience-Landmark, 2022 Backgrounds: Dental avulsion due to trauma, especially in young patients, is a worldwide problem, requiring tooth replacement. Delayed replantation could cause tooth loss when the cementum is severely damaged.
Jiawen Yong +7 more
doaj +2 more sources
Effects of TGF-β1 on OPG/RANKL Expression of Cementoblasts and Osteoblasts Are Similar without Stress but Different with Mechanical Compressive Stress [PDF]
The Scientific World Journal, 2015 Introduction. This study aimed to explore the effects of TGF-β1 on regulating activities of cementoblasts and osteoblasts with or without stress. Material and Methods. Human recombinant TGF-β1 was added with different doses.
Xianrui Yang +11 more
doaj +2 more sources