Results 161 to 170 of about 7,051 (241)

Regenerative periodontal surgery and orthodontic therapy in the treatment of patients with stage IV periodontitis and pathologic tooth migration

Periodontology 2000, EarlyView.
Abstract Background Patients suffering from stage IV periodontitis are often characterized by pathologic tooth migration, drifting, flaring, posterior bite collapse, and secondary occlusal trauma (case type 2). Many times, these patients seek treatment because of functional and esthetic demands.
Karin Jepsen, Christina Tietmann, Peter Proff, Søren Jepsen   +3 more
wiley   +1 more source

Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance

Periodontology 2000, EarlyView.
Abstract Background Periodontal remodeling is a continuous, adaptive process essential for maintaining the structural and functional integrity of periodontal tissues. While external factors such as bacterial biofilm, excessive forces, and poor oral hygiene are recognized triggers of periodontal pathologies, they do not fully explain their persistent ...
Michael Wolf, Ulrike Schulze‐Späte, Thomas Van Dyke, Stefan Wolfart, Thomas Dietrich, Alberto Ortiz, Zhuojun Wu, Joachim Jankowski   +7 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Improving periodontal regeneration outcomes with hyaluronic acid: A systematic review and meta‐analysis

Periodontology 2000, EarlyView.
Abstract Objectives To evaluate the clinical and radiographic efficacy of the adjunctive use of hyaluronic acid (HA) in regenerative periodontal surgery for the treatment of intrabony defects. Materials and Methods A systematic search identified randomized controlled trials (RCTs) involving adult patients with intrabony defects who underwent ...
Abdusalam E. Alrmali, Qasim Omer Butt, Rami Kassar, Parham Hazrati, Yousef Amrou, Anton Sculean, Hom‐Lay Wang   +6 more
wiley   +1 more source

Surgical considerations based on oral and periodontal vascularization

Periodontology 2000, EarlyView.
Abstract Objectives To synthesize current evidence on vascular and anastomotic patterns, emphasizing their operative implications for optimizing flap perfusion, neovascularization, and wound healing in periodontal and implant surgery, while accounting for anatomical variability and collateral circulation. Materials and Methods A comprehensive review of
Arvin Shahbazi, Edward P. Allen, Sebastian Gschwindt, Kevin G. Murphy, Gábor Baksa, Anton Sculean   +5 more
wiley   +1 more source

Metabolic reprogramming of the immune response in periodontitis

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon, Melissa Grant, Iain Chapple, Joao Paulo Steffens   +3 more
wiley   +1 more source

Decoding host–microbial dynamics in peri‐implantitis: Ecosystem‐specific experimental models

Periodontology 2000, EarlyView.
Abstract Background Peri‐implantitis is an inflammatory disease arising within a unique host–microbial–biomaterial ecosystem. Unlike periodontitis, peri‐implant tissues lack a periodontal ligament and epithelial junction integrity and interface with metal oxides on titanium surfaces.
Georgios A. Kotsakis, Davi Araújo, Asaf Wilensky, Juliana Girón Bastidas, Stella Alimperti, Flavia Pirih   +5 more
wiley   +1 more source

Dentifrice formulations for the treatment of dentin hypersensitivity: A systematic review and network meta‐analysis

Periodontology 2000, EarlyView.
Abstract Objectives To update the evidence on the comparative effectiveness of self‐applied dentifrices for the treatment of dentin hypersensitivity (DH) using systematic review and network meta‐analysis methodology. Materials and Methods Randomized controlled trials evaluating self‐applied dentifrices in adults with a diagnosis of DH were identified ...
A. J. Gormley, T. Walsh, J. Twigg, C. Farrugia, A. Pollard, B. Bullock, N. X. West   +6 more
wiley   +1 more source

Platelet Concentrates in Tooth Replantation: A Narrative Review and Evidence Synthesis of Periodontal and Pulpal Healing

Clinical and Experimental Dental Research, Volume 12, Issue 6, December 2026.
ABSTRACT Objectives The prognosis of an avulsed, replanted tooth over the long term hinges on whether the periodontal ligament (PDL) and the dental pulp can be preserved or regenerated. When extra‐oral dry time is prolonged, PDL necrosis follows, and the root becomes prone to inflammatory or replacement (ankylotic) resorption.
Walaa Almarji, Mohannad Laflouf
wiley   +1 more source