Results 41 to 50 of about 291,396 (287)

Mathematical methods and models for radiation carcinogenesis studies [PDF]

open access: yes, 1986
Research on radiation carcinogenesis requires a twofold approach. Studies of primary molecular lesions and subsequent cytogenetic changes are essential, but they cannot at present provide numerical estimates of the risk of small doses of ionizing ...
A.M. Kellerer   +25 more
core   +1 more source

Nonlinear Regression With Censored Data [PDF]

open access: yesTechnometrics, 2007
Suppose that the random vector (X, Y) satisfies the regression model Y = m(X) + σ(X)ϵ, where m (·) = E(Y||·) belongs to some parametric class {mθ(·):θ∈} of regression functions, σ2(·) = var(Y||·) is unknown, and ϵ is independent of X. The response Y is subject to random right censoring, and the covariate X is completely observed.
Heuchenne, Cédric, Van Keilegom, Ingrid
openaire   +3 more sources

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell   +14 more
wiley   +1 more source

Modeling left-truncated and right-censored survival data with longitudinal covariates [PDF]

open access: yes, 2012
There is a surge in medical follow-up studies that include longitudinal covariates in the modeling of survival data. So far, the focus has been largely on right-censored survival data.
Su, Yu-Ru, Wang, Jane-Ling
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

FHtest: An R Package for the Comparison of Survival Curves with Censored Data

open access: yesJournal of Statistical Software, 2017
The Fleming-Harrington class for right-censored data was first introduced by Harrington and Fleming (1982). This class is widely used in survival analysis studies and it is a subset of the so-called weighted logrank test statistics.
Ramon Oller, Klaus Langohr
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Fitting Penalized Estimator for Sparse Covariance Matrix with Left-Censored Data by the EM Algorithm

open access: yesMathematics
Estimating the sparse covariance matrix can effectively identify important features and patterns, and traditional estimation methods require complete data vectors on all subjects.
Shanyi Lin   +4 more
doaj   +1 more source

Cost Analysis With Censored Data [PDF]

open access: yesMedical Care, 2009
Economic evaluation of medical interventions has become an accepted, and often required, adjunct to the standard effectiveness and safety assessment in clinical research. However, the statistical analysis can be challenging due to censored cost data, as commonly obtained in medical studies.
openaire   +2 more sources

Quantile Regression for Doubly Censored Data [PDF]

open access: yesBiometrics, 2011
SummaryDouble censoring often occurs in registry studies when left censoring is present in addition to right censoring. In this work, we propose a new analysis strategy for such doubly censored data by adopting a quantile regression model. We develop computationally simple estimation and inference procedures by appropriately using the embedded ...
Ji, Shuang   +3 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy