Results 41 to 50 of about 294,096 (237)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

FHtest: An R Package for the Comparison of Survival Curves with Censored Data

open access: yesJournal of Statistical Software, 2017
The Fleming-Harrington class for right-censored data was first introduced by Harrington and Fleming (1982). This class is widely used in survival analysis studies and it is a subset of the so-called weighted logrank test statistics.
Ramon Oller, Klaus Langohr
doaj   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Fitting Penalized Estimator for Sparse Covariance Matrix with Left-Censored Data by the EM Algorithm

open access: yesMathematics
Estimating the sparse covariance matrix can effectively identify important features and patterns, and traditional estimation methods require complete data vectors on all subjects.
Shanyi Lin   +4 more
doaj   +1 more source

Impact of Censored or Penalized Data in the Genetic Evaluation of Two Longevity Indicator Traits Using Random Regression Models in North American Angus Cattle

open access: yesAnimals, 2021
This study aimed to evaluate the impact of different proportions (i.e., 20%, 40%, 60% and 80%) of censored (CEN) or penalized (PEN) data in the prediction of breeding values (EBVs), genetic parameters, and computational efficiency for two longevity ...
Hinayah R. Oliveira   +3 more
doaj   +1 more source

The Liability Threshold Model for Censored Twin Data

open access: yes, 2015
Family studies provide an important tool for understanding etiology of diseases, with the key aim of discovering evidence of family aggregation and to determine if such aggregation can be attributed to genetic components.
Hjelmborg, Jacob B.   +2 more
core   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu   +5 more
wiley   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller   +6 more
wiley   +1 more source

An EM algorithm for GMM parameter estimation in the presence of censored and dropped data with potential application for indoor positioning

open access: yesICT Express, 2019
In this paper, a specific type of incomplete data in Wi-Fi fingerprinting based indoor positioning systems (WF-IPS) is presented: censored and dropped mixture data. For fitting this type of data, a censored and dropped Gaussian Mixture Model (CD-GMM) was
Trung Kien Vu   +2 more
doaj   +1 more source

Alternative measures to evaluate the accuracy and bias of genomic predictions with censored records

open access: yesActa Scientiarum: Animal Sciences, 2023
This study aimed to propose and compare metrics of accuracy and bias of genomic prediction of breeding values for traits with censored data. Genotypic and censored-phenotypic information were simulated for four traits with QTL heritability and polygenic
Geraldo Magela da Cruz Pereira   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy