Results 41 to 50 of about 201,170 (293)

Single-Index Quantile Regression Models for Censored Data [PDF]

, 2021
When the dimension of the covariate space is high, semiparametric regression models become indispensable to gain flexibility while avoiding the curse of dimensionality. These considerations become even more important for incomplete data. In this work, we consider the estimation of a semiparametric single-index model for conditional quantiles with ...
Bücher, Axel, El Ghouch, Anouar, Van Keilegom, Ingrid   +2 more
openaire   +3 more sources

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

New Flexible Regression Models Generated by Gamma Random Variables with Censored Data [PDF]

, 2016
We propose and study a new log-gamma Weibull regression model. We obtain explicit expressions for the raw and incomplete moments, quantile and generating functions and mean deviations of the log-gamma Weibull distribution.
Cordeiro, Gauss M., Hamedani, Gholamhossein G., Hashimoto, Elizabeth M., Ortega, Edwin M. M.   +3 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Enhancing uncertainty quantification in drug discovery with censored regression labels

Artificial Intelligence in the Life Sciences
In the early stages of drug discovery, decisions regarding which experiments to pursue can be influenced by computational models for quantitative structure–activity relationships (QSAR).
Emma Svensson, Hannah Rosa Friesacher, Susanne Winiwarter, Lewis Mervin, Adam Arany, Ola Engkvist   +5 more
doaj   +1 more source

Likelihood Inference In Parallel Systems Regression Models With Censored Data [PDF]

, 1997
The work in this thesis is concerned with the investigation of the finite sample performance of asymptotic inference procedures based on the likelihood function when applied to the regression model based on parallel systems with censored data.
S.M.Baklizi, Ayman
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The Log-Beta Generalized Half-Normal Regression Model [PDF]

Journal of Statistical Theory and Applications (JSTA), 2013
We introduce a log-linear regression model based on the beta generalized half-normal distribution (Pescim et al., 2010).We formulate and develop a log-linear model using a new distribution so-called the log-beta general- ized half normal distribution.We ...
Rodrigo R. Pescim, Edwin M.M. Ortega, Gauss M. Cordeiro, Clarice G.B. Demtrio, G.G. Hamedani   +4 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Censored Bimodal Symmetric-Asymmetric Alpha-Power Model

Revista Colombiana de Estadística, 2013
We introduce the censored bimodal symmetric-asymmetric alpha-power models to adjust censored data with bimodality and high levels of skewness and kurtosis. The moments corresponding are computed, the maximum likelihood estimation for the model parameters
HUGO S. SALINAS, GUILLERMO MARTÍNEZ-FLÓREZ, GERMÁN MORENO-ARENAS   +2 more
doaj