Results 41 to 50 of about 100,255 (311)
Flexible Boosting of Accelerated Failure Time Models [PDF]
, 2008 When boosting algorithms are used for building survival models from high-dimensional data, it is common to fit a Cox proportional hazards model or to apply semiparametric least squares techniques.
Torsten Hothorn +5 more
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Nonparametric predictive inference with right-censored data [PDF]
, 2002 This thesis considers nonparametric predictive inference for lifetime data that include right-censored observations. The assumption A((_m)) proposed by Hill in 1968 provides a partially specified predictive distribution for a future observation given ...
Yan, Ke-Jian
core
A multiparameter regression model for interval‐censored survival data [PDF]
Statistics in Medicine, 2020 We develop flexible multiparameter regression (MPR) survival models for interval‐censored survival data arising in longitudinal prospective studies and longitudinal randomised controlled clinical trials. A multiparameter Weibull regression survival model, which is wholly parametric, and has nonproportional hazards, is the main focus of the article.
Defen Peng +2 more
openaire +3 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Enhancing uncertainty quantification in drug discovery with censored regression labels
Artificial Intelligence in the Life SciencesIn the early stages of drug discovery, decisions regarding which experiments to pursue can be influenced by computational models for quantitative structure–activity relationships (QSAR).
Emma Svensson +5 more
doaj +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Censored Bimodal Symmetric-Asymmetric Alpha-Power Model
Revista Colombiana de Estadística, 2013 We introduce the censored bimodal symmetric-asymmetric alpha-power models to adjust censored data with bimodality and high levels of skewness and kurtosis. The moments corresponding are computed, the maximum likelihood estimation for the model parameters
HUGO S. SALINAS +2 more
doaj
A Cox‐Aalen Model for Interval‐censored Data [PDF]
Scandinavian Journal of Statistics, 2014 AbstractThe Cox‐Aalen model, obtained by replacing the baseline hazard function in the well‐known Cox model with a covariate‐dependent Aalen model, allows for both fixed and dynamic covariate effects. In this paper, we examine maximum likelihood estimation for a Cox‐Aalen model based on interval‐censored failure times with fixed covariates.
Cook, Richard J., Boruvka, Audrey
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source