Results 111 to 120 of about 7,077,115 (219)

Correction: How pain intensity and mental disorders shape chronic pain sick leave and quality of life in the general Spanish population. [PDF]

Sci Rep
Neumann C, Hartung TJ, Boje K, Bahmer T, Keil J, Lieb W, Franzpoetter K, Welzel J, Chaplinskaya-Sobol I, Endres M, Geritz J, Haeusler KG, Heuschmann P, Hinz A, Pütz SM, Schäfer A, Nuernberger C, Schmidbauer L, Krawczak M, Ruß AK, Krist L, Keil T, Kudelka J, Maetzler C, Mehnert-Theuerkauf A, Montellano FA, Morbach C, Schmidt S, Heyckendorf J, Steigerwald F, Stoerk S, Lemhoefer C, Schreiber S, Finke C, Maetzler W.   +34 more
europepmc   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Correction: Molecular subtypes and the (in vitro) response of glioblastoma to temozolomide. [PDF]

BJC Rep
Rancati S, Campolungo M, Duarte Dalmolin G, Lau P, Furia F, Coppe A, Landuzzi F, Vecchi M, Cavalli A, Gustincich S, Tirelli N.   +10 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Psychometric evaluation of the NFOSI-18 disease related symptoms - Physical, NFOSI-18 Total, and FACT GP5 in the recurrent ovarian cancer phase III study GY004. [PDF]

Gynecol Oncol
Tang X, Huang H, Peipert JD, Zola A, Buscema J, Yang K, Tew W, O'Cearbhaill RE, Muller C, Goodheart MJ, Moore RG, Liu R, Geller MA, Michener C, Chan J, Carney M, McNally L, Street D, Bookman MA, Moore KN, Liu JF, Wenzel L, Cella D.   +22 more
europepmc   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Addressing Biases in Analysis of Time of Infusion: NCI/SWOG Trial S1404 Among Participants With High-Risk Resectable Melanoma Who Received Adjuvant Anti-PD-1 Therapy. [PDF]

JCO Oncol Pract
Othus M, Truong TG, Sharon E, Kendra K, Grossmann K, Buchbinder E, Khushalani NI, Eroglu Z, Chandra S, Doolittle GC, Kirkwood JM, Ikeguchi A, Mihalcioiu C, Cowey CL, Reddy SA, Johnson DB, Taylor M, Sondak VK, Ribas A, Patel SP.   +19 more
europepmc   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Correction: Real-World Outcomes for Patients with Clinically Node-Positive Melanoma Undergoing Neoadjuvant Immunotherapy and Nodal Dissection. [PDF]

Ann Surg Oncol
Herb J, Bassett RL, Torres-Cabala CA, Prieto VG, Patel SP, Holder AM, Fisher SB, Lucci A, Wargo J, Amaria RN, Davies MA, Glitza Oliva IC, Tawbi HA, McQuade J, Ikeguchi AP, Wong MK, Diab AK, Gershenwald JE, Ross MI, Weiser R.   +19 more
europepmc   +1 more source