Results 211 to 220 of about 16,760,378 (317)

Human Immunodeficiency Virus-Associated Proteomic Signature of Myocardial Fibrosis and Incident Heart Failure. [PDF]

J Infect Dis
Peterson TE, Hahn VS, Moaddel R, Zhu M, Fan J, De S, Haberlen SA, Palella FJ, Plankey M, Bader JS, Lima JAC, Gerszten RE, Rotter JI, Kirk GD, Piggott DA, Ferrucci L, Margolick JB, Brown TT, Post WS, Wu KC.   +19 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Embedding Music in Care at Mayo Clinic. [PDF]

Mayo Clin Proc Innov Qual Outcomes
Van Buren KJ, Wood C, Mensink SA, Le BN.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Risk Factors for Discordance Between Synovial Fluid Culture and Intraoperative Cultures in Revision Arthroplasties: Results From a European Multicentre Observational Study. [PDF]

JB JS Open Access
Ottink KD, Olearo F, Vaznaisiene D, Rolvien T, Kaoual S, Morreel E, Bîrluţiu V, Gómez-Junyent J, Lindberg-Larsen M, Reissier S, Rossi N, Dolores Del Toro Lopez M, Widerström M, Fernandez Sampedro M, Veltman ES, Petersdorf S, Rohde H, Wouthuyzen-Bakker M.   +17 more
europepmc   +1 more source

HEALTH CENTERS

American Journal of Public Health, 1919
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Author Correction: A Bayesian decision support system for automated insulin doses in adults with type 1 diabetes on multiple daily injections: a randomized controlled trial. [PDF]

Nat Commun
Kobayati A, El Fathi A, Garfield N, Legault L, Jafar A, Yale JF, Tsoukas MA, Haidar A.   +7 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source