Results 71 to 80 of about 7,077,115 (219)
The Children’s Learning Center
Voices in Bioethics, 2014 Your smallest decision can make the biggest difference in learning. Recently, I became a member of the New York City Teaching Fellows Program’s 25th cohort. My area of specialization is in special education. More than half of this year’s teaching fellows
Obiora Anekwe
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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The phase portrait of the Hamiltonian system associated to a Pinchuk map
Anais da Academia Brasileira de CiênciasIn this paper we describe the global phase portrait of the Hamiltonian system associated to a Pinchuk map in the Poincaré disc. In particular, we prove that this phase portrait has 15 separatrices, five of them singular points, and 7 canonical regions ...
JOAN CARLES ARTÉS +2 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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International Journal of CommunicationThe digital public sphere is characterized by seemingly paradoxical tensions between centers and peripheries: While some actors leverage the affordances of digital platforms to garner attention and gain prominence in public discourse, others prefer to ...
Patrick Donges +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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DECISION-MAKING PROCESS IN INFORMATION CENTER
Zeitschrift für die Welt der Türken, 2010 Decision-making is a process that directly effects all functions of management. For that reason, this process has got charecteristic effect directly on whole orgnaizational activity.
Mustafa TALAS, Malik YILMAZ
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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