Results 151 to 160 of about 1,465,301 (281)

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

open access: yesFEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda   +7 more
wiley   +1 more source

A graph theory-based algorithm for the reduction of atmospheric chemical mechanisms. [PDF]

open access: yesPNAS Nexus
Wiser F   +11 more
europepmc   +1 more source

Designing and Delivering Effective Faculty Development With the Adult Learner in Mind

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT University faculty are busy professionals tasked with many different responsibilities. While they certainly care about student success, their expertise is generally discipline‐specific and strategies for effective and engaging teaching are developed in the classroom along the way.
Nancy V. Winfrey
wiley   +1 more source

Instructional Design and Facilitation for Multigenerational Online Learning in Higher Education—Baby Boomers, Generation X, Millennials, and Generation Z

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Nontraditional students represent a substantial number and significant percentage of students in higher education. While these adult learners have similarities, they also span 50+ years with generational differences. At the same time, online learning is on the rise, offering opportunities and challenges for nontraditional students and those ...
Brittany Hyden, Catherine A. Cherrstrom
wiley   +1 more source

Designing a spatial pattern to rebalance the orientation of development and protection in Wuhan

open access: yesJournal of Geographical Science, 2020
G. Jin   +5 more
semanticscholar   +1 more source

Patterns of social participation among older adults and their association with self-rated health: the mediating role of activities of daily living. [PDF]

open access: yesAging Clin Exp Res
Zhou J   +13 more
europepmc   +1 more source

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