Results 91 to 100 of about 4,711,203 (306)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

An algorithm for symbolic computation of center manifolds [PDF]

, 1989
A useful technique for the study of local bifurcations is the center manifold theory because a dimensional reduction is achieved. The computation of Taylor series approximations of center manifolds gives rise to several difficulties regarding the operational complexity and the computational effort.
Emilio Freire, Estanislao Gamero, Enrique Ponce, Leopoldo García Franquelo   +3 more
openaire   +3 more sources

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Euclidean decompositions of hyperbolic manifolds and their duals [PDF]

, 2007
Epstein and Penner constructed in [EP88] the Euclidean decomposition of a non-compact hyperbolic n-manifold of finite volume for a choice of cusps, n >= 2. The manifold is cut along geodesic hyperplanes into hyperbolic ideal convex polyhedra.
Lukac, Sascha Georg
core  

Bott–Chern cohomology and q-complete domains [PDF]

, 2013
In studying the Bott–Chern and Aeppli cohomologies for q-complete manifolds, we introduce the class of cohomologically Bott–Chern q-complete ...
Daniele Angella, Angella, Daniele, Calamai, Simone, Simone Calamai   +3 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Flat connections in a domain of projective space

Дифференциальная геометрия многообразий фигур
The theory of connections of manifolds has wide application in ma­the­matics and physics. Flat connection affects the type of parallel translations. In the present paper, we study the curvature and torsion of connec­tions on the Grassmann manifold ...
O. O. Belova
doaj   +1 more source

Development and implementation of ISAR, a new synthesis platform for radiopharmaceutical production

EJNMMI Radiopharmacy and Chemistry, 2019
Background PET radiopharmaceutical development and the implementation of a production method on a synthesis module is a complex and time-intensive task since new synthesis methods must be adapted to the confines of the synthesis platform in use. Commonly
Christopher Frank, Georg Winter, Fredrik Rensei, Victor Samper, Allen F. Brooks, Brian G. Hockley, Bradford D. Henderson, Christian Rensch, Peter J. H. Scott   +8 more
doaj   +1 more source

Center manifolds without a phase space

Transactions of the American Mathematical Society, 2018
We establish center manifold theorems that allow one to study the bifurcation of small solutions from a trivial state in systems of functional equations posed on the real line. The class of equations includes most importantly nonlinear equations with nonlocal coupling through convolution operators as they arise in the description of spatially extended ...
Faye, Grégory, Scheel, Arnd
openaire   +4 more sources