Results 161 to 170 of about 3,380,250 (279)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
BACKGROUND AND AIM: Root canal treatment, especially in curved and constricted root canals, can be very difficult and time consuming. Several investigations have compared the reciprocating and full sequence motions in terms of shaping ability.
Shahriar Shahab +4 more
core
Canal transportation and centering ability of root canals prepared using rotary and reciprocating systems with and without PathFiles in cone-beam computed tomography-based three-dimensional molar prototypes. [PDF]
Sunildath MS +5 more
europepmc +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Multidimensional Analysis of Canal Transportation and Centering Ability of WaveOne Gold and ProTaper Next File Systems in Curved Root Canals. [PDF]
Tanveer SA, Ghafoor R.
europepmc +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The Centering Pregnancy Program
The Centering Pregnancy Program (Murrels Inlet ...
Haugh, Taylor
core +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source

