Comparative evaluation of canal transportation and canal centering ability in oval canals with newer nickel-titanium rotary single file systems - A cone-beam computed tomography study. [PDF]
Manocha SK +5 more
europepmc +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Effect of Different Downward Loads on Canal Centering Ability, Vertical Force, and Torque Generation during Nickel-Titanium Rotary Instrumentation. [PDF]
Maki K +6 more
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Effect of Rotational Modes on Torque/Force Generation and Canal Centering Ability during Rotary Root Canal Instrumentation with Differently Heat-Treated Nickel-Titanium Instruments. [PDF]
Omori S +9 more
europepmc +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Transportation and Centering Ability of Kedo-S Pediatric and Mtwo Instruments in Primary Teeth: A Cone-beam ComputedTomography Study. [PDF]
Haridoss S, Rakkesh KM, Swaminathan K.
europepmc +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Comparison of Canal Transportation and Centering Ability of One-G, EdgeGlidePath, and Neolix: A MicroComputed Tomography Study of Curved Root Canals. [PDF]
Shojaeian S +6 more
europepmc +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source

