Results 131 to 140 of about 3,380,250 (279)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Contemplative and Centering Prayer
, 2014 Centering prayer was developed to make accessible the rich Christian contemplative prayer tradition to young North American spiritual seekers. In the fifty years since its development it has become the centerpiece of an international movement, which ...
James C. Wilhoit
core +1 more source
EndodontologyAim: The aim of this study was to assess the apical transportation and centering efficacy of ProTaper Ultimate (PTU) and ProTaper Next (PTN) by micro-computed tomography (micro-CT) analysis.
Palak Jitesh Gandhi +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Enhanced pitch centering in individuals with laryngeal dystonia
Frontiers in Human NeuroscienceIntroductionLaryngeal dystonia (LD) is a neurological voice disorder marked by strained voice quality, pitch instability, and sudden voice breaks, yet the mechanisms underlying impaired vocal control are poorly understood. One key process, known as pitch
Rabab Rangwala +13 more
doaj +1 more source
A cone-beam computed tomographic analysis of total dentin removed, canal transportation, and canal-centering ability following instrumentation with three different file systems: An in vitro study. [PDF]
J Conserv Dent Endod, 2023 Khandeparkar ANS +2 more
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
An Interpretative Phenomenological Analysis of Centering Prayer
, 2018 Centering prayer is a contemplative practice designed to facilitate psychological and spiritual growth and development. It is currently being practiced in Christian communities and faith-based organizations around the world. Despite the widespread appeal
Rhodes, Charles D.
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source