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Bioactive Peptides and Proteins from Centipede Venoms

open access: yesMolecules, 2022
Venoms are a complex cocktail of biologically active molecules, including peptides, proteins, polyamide, and enzymes widely produced by venomous organisms.
Yalan Han   +2 more
exaly   +4 more sources

Isolation and characterization of the major centipede allergen Sco m 5 from Scolopendra subspinipes mutilans

open access: yesAllergology International, 2021
Background: Allergic reactions have been observed following both direct centipede bites and the clinical use of centipede-containing medicines, such as traditional Chinese medicines utilizing Scolopendra subspinipes mutilans; however, no natural ...
Feng Zhao, Qi-Quan Wang, Yun Zhang
exaly   +4 more sources

Centipede Venom Peptides Acting on Ion Channels

open access: yesToxins, 2020
Centipedes are among the oldest venomous arthropods that use their venom to subdue the prey. The major components of centipede venom are a variety of low-molecular-weight peptide toxins that have evolved to target voltage-gated ion channels to interfere ...
Yanyan Chu, Peiju Qiu, Rilei Yu
exaly   +4 more sources

Effectiveness of antibiotic prophylaxis in patients with centipede stings: a randomized controlled trial [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2021
Objective Centipede stings are a common problem in tropical countries. Current treatment guidelines do not include recommendations for antibiotic prophylaxis to prevent the associated bacterial infection since no previous study has assessed the ...
Chanon Changratanakorn   +7 more
doaj   +2 more sources

Effect of leech-centipede medicine on improving erectile function in diabetes-induced erectile dysfunction rats via PDE5 signalling pathway-related molecules

open access: yesPharmaceutical Biology, 2021
Context The leech and centipede granules have good curative effects on many diabetic vascular diseases, including diabetes-induced erectile dysfunction (DIED).
Ji-Sheng Wang   +9 more
doaj   +2 more sources

The arylsulfatase- and phospholipase-rich venom of the plutoniumid centipede Theatops posticus

open access: yesToxicon, 2023
Research on centipede venoms has led to the discovery of a diverse array of novel proteins and peptides, including those with homology to previously discovered toxin families (e.g., phospholipase A2s and pM12a metalloproteases) and novel toxin families ...
Schyler A Ellsworth   +2 more
exaly   +2 more sources

Adaptive Centipede Walking via Synergetic Coupling Between Decentralized Control and Flexible Body Dynamics

open access: yesFrontiers in Robotics and AI, 2022
Multi-legged animals such as myriapods can locomote on unstructured rough terrain using their flexible bodies and legs. This highly adaptive locomotion emerges through the dynamic interactions between an animal’s nervous system, its flexible body, and ...
Kotaro Yasui   +5 more
doaj   +2 more sources

Centipede Venom: A Potential Source of Ion Channel Modulators

open access: yesInternational Journal of Molecular Sciences, 2022
Centipedes are one of the most ancient and successful living venomous animals. They have evolved spooky venoms to deter predators or hunt prey, and are widely distributed throughout the world besides Antarctica.
Peter Muiruri Kamau, Ren Lai, Lei Luo
exaly   +2 more sources

Centipede Venom: Recent Discoveries and Current State of Knowledge

open access: yesToxins, 2015
Centipedes are among the oldest extant venomous predators on the planet. Armed with a pair of modified, venom-bearing limbs, they are an important group of predatory arthropods and are infamous for their ability to deliver painful stings.
Eivind A B Undheim   +2 more
exaly   +3 more sources

A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins

open access: yesStructure, 2019
Disulfide-rich peptides (DRPs) play diverse physiological roles and have emerged as attractive sources of pharmacological tools and drug leads. Here we describe the 3D structure of a centipede venom peptide, U-SLPTX15-Sm2a, whose family defines a unique ...
Thomas Shafee   +2 more
exaly   +2 more sources

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