Results 91 to 100 of about 18,273,946 (366)
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Flight to the East: memorial architecture of early Central Asia
, 2020 Independent reseacher, Alexey Akulov
openalex +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Paleomagnetic and rock magnetic evidence for a secondary yet early magnetization in large sandstone pipes and host Late Middle Jurassic (Callovian) Summerville Formation and Bluff Sandstone near Mesita, west central New Mexico [PDF]
, 2004 J. W. Geissman, Stephen S. Harlan
openalex +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
APIK Journal of Internal MedicineBackground: Obesity is a major risk factor for metabolic and age-related diseases, yet its association with biological ageing remains unclear. Telomere length is a recognized biomarker of cellular ageing, and adipokines, such as leptin, may play a role ...
Madhav Prabhu +2 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Challenges related to the implementation of the CCMDD programme in Sekhukhune clinics
Health SA Gesondheid: Journal of Interdisciplinary Health SciencesBackground: Implementation of the central chronic medicines dispensing and distribution (CCMDD) programme in most of Sekhukhune primary health care (PHC) has been challenging.
Ragosebo P. Sekopa +1 more
doaj +1 more source