Results 71 to 80 of about 4,741,798 (267)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Assessment of Effect of Flux Scheme and Turbulence Model on Blade-to-blade Calculations [PDF]

open access: yesJournal of Applied Fluid Mechanics
Today, due to advances in computing power, Reynolds Averaged Navier-Stokes (RANS) solvers are widely preferred for quasi-three-dimensional (Q3D) blade-to-blade analysis.
M. Bilgiç, Ö. U. Baran, M. H. Aksel
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Central Processes Underlying Fibromyalgia

open access: yesEuropean Medical Journal, 2018
Fibromyalgia is a common chronic pain disorder characterised by a robust clinical phenotype with principal features that include widespread pain and tenderness, as well as high levels of sleep disturbance, fatigue, cognitive dysfunction, and emotional ...
Geoffrey Littlejohn, Emma Guymer
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Corticospinal, reticulospinal and motoneuronal contributions to fatigability during a sustained contraction of the elbow flexors

open access: yesExperimental Physiology
Synaptic input to the motoneuron pool is altered during fatiguing muscle contractions. In humans, the corticospinal tract is often studied, with equivocal findings regarding its role in the reduction of force.
Oliver Hayman   +8 more
doaj   +1 more source

Prognosis of Early Stage Cervical Cancer According to Patterns of Recurrence

open access: yesCancer Management and Research, 2021
Yuanyuan Chen,1,2 Yiming Zhu,3 Jinchang Wu1 1Department of Radiation, The Affiliated Suzhou Hospital of Nanjing Medical University and Second Affiliated Hospital of Xuzhou Medical University, Suzhou, Jiangsu, People’s Republic of China; 2Department of ...
Chen Y, Zhu Y, Wu J
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Epidemiology and Prognosis of Patients With Osteosarcoma at Different Primary Sites: A SEER Population‐Based Study

open access: yesCancer Reports
Background Osteosarcoma is a primary bone malignancy with a known bimodal age distribution. However, epidemiological patterns based on precise primary anatomical sites are not well characterized.
Jianqun Wang   +8 more
doaj   +1 more source

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