Results 131 to 140 of about 3,136,050 (295)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Fear and loathing of central banks in America [PDF]
The Federal Reserve System is America’s uneasy compromise between our dislike of concentrated financial power and our desire to promote efficiency in our national payments system.
Bruce Champ, Michael F. Bryan
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
How does the North American Free Trade Agreement (NAFTA) affect Central America? [PDF]
Most Central American economies experienced slower growth in the 1980s than in the 1960s and 1970s, trailing far behind the Asian Tigers. Contributing to slow growth were severe external shocks, sizable macroeconomic disturbances, and widespread ...
Guerra, Alfonso +3 more
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The Culicoides (Diptera: Ceratopogonidae) of Belize, Central America [PDF]
, 1999 The Culicoides fauna of Belize is poorly known, and until 197 4 only 3 species were recorded. Nineteen species of Culicoides from Belize were identified from six collection sites: C. barbosai Wirth & Blanton, C. crepuscularis Malloch, C.
Brickle, Deborah S., Hagan, Daniel V.
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Civil society in poverty alleviation: perspectives from Tanzania, Ethiopia and Central America [PDF]
, 2007 Although donor discourse on international development policy places less emphasis on civil society than formerly this paper present evidence from Tanzania, Ethiopia and Central America that aid for civil society has had a positive effect on the capacity ...
Connolly, Eileen
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Have US-Funded CARSI Programs Reduced Crime and Violence in Central America? An Examination of LAPOP'S Impact Assessment of US Violence Prevention Programs in Central America [PDF]
, 2016 In October 2014, the Latin American Public Opinion Project (LAPOP) at Vanderbilt University published an impact assessment study of community-based violence prevention programs that have been implemented under the umbrella of the US State Department's ...
Alexander Main +2 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source