Results 131 to 140 of about 612,154 (305)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Overseas Relief, Africa: North Africa (ASF AR 1, Box 1, Folder 14)
, 1945 Digital ImageDigital finding aid ...
Central Sephardic Jewish Community of America
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Overseas Relief, Africa: Tripoli (ASF AR 1, Box 1, Folder 15)
, 1947 Digital ImageDigital finding aid ...
Central Sephardic Jewish Community of America
core
Coffee Rust Fungus Threatens Employment Collapse in Central America [PDF]
, 2014 Coffee rust is having a serious impact on the livelihoods of hundreds of thousands of poor people in Central America who earn their income from growing coffee or working on coffee farms.
Magrath, John
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Immigration (ASF AR 1, Box 1, Folder 5)
, 1948 Digital ImageDigital finding aid ...
Central Sephardic Jewish Community of America
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Overseas Relief (ASF AR 1, Box 1, Folder 13)
, 1948 Digital ImageDigital finding aid ...
Central Sephardic Jewish Community of America
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source