Results 111 to 120 of about 3,136,050 (295)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

New record of Clypeasterophilus stebbingi (Rathbun, 1918) (Decapoda: Brachyura: Pinnotheridae) from the east coast of Nicaragua

open access: yesNauplius
The pinnotherid crab Clypeasterophilus stebbingi (Rathbun, 1918), previously known from Florida, USA, Colombia and Brazil, is reported for the first time from Central America, on the east coast of Nicaragua.
Michel E. Hendrickx, Francisco Solis
doaj  

Environmental, economic, and social changes in rural America visible in survey data and satellite images [PDF]

open access: yes, 2011
This brief focuses on the changing landscapes of different types of rural America where social, economic, and ecological changes are occurring over large areas: the Northern Forest, Central Appalachia, and the Pacific Northwest.
Colocousis, Chris R., Hartter, Joel N.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Any Link Between Legal Central Bank Independence and Inflation? Evidence from Latin America and the Caribbean [PDF]

open access: yes
This paper reviews central bank legislation in 24 countries in Latin America and the Caribbean during the 1990s. Using panel regressions, the paper finds a negative relationship between legal central bank independence (CBI) and inflation.
Francisco Vázquez, Luis Jácome
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Coping with the “coffee crisis” in Central America [PDF]

open access: yes
"This study examines the effect of a safety-net program on households' well-being and work activities during an economic downturn. It considers (1) how rural Nicaraguan households without the Red de Protección Social (RPS) program fared over the period ...
Maluccio, John A.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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