Results 101 to 110 of about 3,136,050 (295)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Phase Locking of the Boreal Summer Atmospheric Response to Dry Land Surface Anomalies in the Northern Hemisphere [PDF]
Past modeling simulations, supported by observational composites, indicate that during boreal summer, dry soil moisture anomalies in very different locations within the United States continental interior tend to induce the same upper-tropospheric ...
Chang, Yehui +3 more
core +1 more source
Earning Their Way out of Poverty (Outline and Sample Chapter) [PDF]
[Excerpt] According to the latest figures, today an estimated 3.1 billion people still live in absolute poverty, essentially all of them in the low- and middle-income countries of Asia, Latin America, and Africa and none of them in what are traditionally
Fields, Gary S
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Glyptostrobus europaeus (Brongn.) Heer in Arkansas [PDF]
Glyptostrobus europaeus (Brongn.) Heer, a fossil gymnosperm is found at a few locations in central North America, in deposits of the Eocene. This work cites previously reported localities and reports a new site at Hooker, Arkansas.
Wittlake, Eugene B.
core +2 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The History, Present Condition, and Future of the Molluscan Fisheries of North and Central American and Europe: Volume 1, Atlantic and Gulf Coasts [PDF]
This three-volume monograph represents the first major attempt in over a century to provide, on regional bases, broad surveys of the history, present condition, and future of the important shellfisheries of North and Central America and Europe.
Burrell, Jr., Victor G. +3 more
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