Results 81 to 90 of about 7,515,240 (216)
Requests for Assistance, Individuals (ASF AR 1, Box 1, Folder 34)
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Central Sephardic Jewish Community of America
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Background Honduras has historically faced major barriers to building a sustainable health research system, including minimal R&D investment and limited institutional infrastructure. A Canadian-funded initiative (2007–2012) established the first research-
Gustavo Fontecha +4 more
doaj +1 more source
Employment: Requests of the Community (ASF AR 1, Box 1, Folder 4)
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Central Sephardic Jewish Community of America
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Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Central America Options for the Poor [PDF]
Oxfam has worked alongside poor people in Central America for more than 25 years, through wars, earthquakes and revolutions. In up-to-date and readable form, this book presents the background to the current social and political crises in the region ...
MacDonald, Neil
core +1 more source
Immigration: Inactive (ASF AR 1, Box 1, Folder 6)
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Central Sephardic Jewish Community of America
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Chronic kidney disease (CKD) of unknown etiology (CKDu) was first reported in El Salvador and Nicaragua in Central America, where it has very high prevalence and mortality. However, CKDu is now an epidemic in countries around the equator: Central America
Karin Broberg
doaj +1 more source
Overseas Relief, Europe: Bulgaria (ASF AR 1, Box 1, Folder 20)
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Central Sephardic Jewish Community of America
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