Results 91 to 100 of about 7,515,240 (216)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Locations: M (ASF AR 1, Box 2, Folder 1)
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Central Sephardic Jewish Community of America
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Overseas Relief, Asia: China (ASF AR 1, Box 1, Folder 16)
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Central Sephardic Jewish Community of America
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Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Homecoming parade float; Phi Beta float; "Central Will Star"; one female student sitting on float
Homecoming parade float built by Phi Beta float carries a female student passenger in costume through Fayette, Mo. The float reads, "Central Will Star".
Central Methodist University, Smiley Memorial Library
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Locations: B (ASF AR 1, Box 1, Folder 43)
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Central Sephardic Jewish Community of America
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Are civil wars to blame for crime in Central America?
The countries of Central America are high up on the list of nations with the highest crime rates in the world. According to the literature, the most common argument is that these high crime rates are a legacy of the armed conflicts of the 1980s.
Ana Sofia Cardenal Izquierdo
doaj
Record of Assistance Requests (ASF AR 1, Box 1, Folder 30)
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Central Sephardic Jewish Community of America
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