Results 91 to 100 of about 612,154 (305)
Overseas Relief, Europe: Bulgaria (ASF AR 1, Box 1, Folder 20)
, 1945 Digital ImageDigital finding aid ...
Central Sephardic Jewish Community of America
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Scandinavian Journal of Work, Environment & Health, 2018 Chronic kidney disease (CKD) of unknown etiology (CKDu) was first reported in El Salvador and Nicaragua in Central America, where it has very high prevalence and mortality. However, CKDu is now an epidemic in countries around the equator: Central America
Karin Broberg
doaj +1 more source
Record of Assistance Requests (ASF AR 1, Box 1, Folder 30)
, 1947 Digital ImageDigital finding aid ...
Central Sephardic Jewish Community of America
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Requests for Assistance from Other Organizations (ASF AR 1, Box 1, Folder 32)
, 1944 Digital ImageDigital finding aid ...
Central Sephardic Jewish Community of America
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Locations: S-Z (ASF AR 1, Box 2, Folder 5)
, 1943 Digital ImageDigital finding aid ...
Central Sephardic Jewish Community of America
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Locations: A (ASF AR 1, Box 1, Folder 40)
, 1945 Digital ImageDigital finding aid ...
Central Sephardic Jewish Community of America
core